Search for dissertations about: "antigenic peptide"

Showing result 11 - 15 of 41 swedish dissertations containing the words antigenic peptide.

  2. 11. CD8+ T cell specificity in thymic selection and in the recognition of antigen

    Author : Johan Sandberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : T cell; specificity; MHC class 1; selection; tolerance;

    Abstract : Specificity mediated by the T cell receptor (TCR) is of fundamental importance for the ability of T cells to function, and regulate humoral immunity and effector mechanisms of the innate immune system. T cells recognize composite molecules consisting of products of the major histocompatibility complex (MHC) class I or class 11 loci, in complex with a short peptide fragment derived from endogenous or antigenic proteins. READ MORE

  4. 12. Immunobiochemical significance of Trypanosoma rangeli in the study of Trypanosoma cruzi

    Author : Azael Patiño Saldaña; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Trypanosoma rangeli is a haemoflagellate that infects humans nonpathogenically in some areas in which T. cruzi, the causative agent of Chagas' disease, is endemic. Since common biological and immunochemical characteristics have been described for these parasites, a detailed study of their relationship is needed. READ MORE

  5. 13. The use of peptides for studying molecular events in HIV- and HSV-infections

    Author : Michael Levi; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Synthetic peptides were used as tools in order to study various characteristic sof human immunodeficiency virus (HIV) and herpes simplex virus (HSV). Peptides were designed as multiple antigenic peptides (MAPs) and used as HIV vaccines in experimental animals. The included HIV epitopes were more immunogenic when immunized as MAPs than as a protein. READ MORE

  6. 14. Exploring the complexity of functional hiv-1 specific t-cell responses and global virus-host genetic variability

    Author : Carina Pérez; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : HIV has become one of the biggest health problems up to date. After 30 years of tremendous effort, the development of an HIV vaccine is still far from achieved. One of the main issues is the high mutation rate of the virus which results in the selection of mutated variants. READ MORE

  7. 15. Structural and Functional Studies on Posttranslational Modifications of Collagen type II in Rheumatoid Arthritis

    Author : Hüseyin Uysal; Biokemi och Strukturbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : The molecular mechanisms behind the development and progression of rheumatoid arthritis are not known in fine details. Both humoral and cellular responses against collagen type II in joint cartilage seems to be important for the disease development. READ MORE