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Showing result 1 - 5 of 28 swedish dissertations matching the above criteria.

  2. 1. Antigenic variation in relapsing fever Borrelia

    Author : Nils Burman; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Borrelia; Relapsing fever; Antigenic variation; Vmp lipoprotein; Rosetting;

    Abstract : The spirochete Borrelia hermsii avoids the immune response of its mammalian host through multiphasic antigenic variation. Serotype specificity is determined by Variable major proteins (Vmp), in the outer membrane. READ MORE

  4. 2. Streptococcal M protein and human C4BP

    Author : Jenny J Persson; Avdelningen för medicinsk mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Infektioner; Infections; Medicin människa och djur ; Medicine human and vertebrates ; human C4BP; M protein; antigenic variation; sequence variability; Streptococcus pyogenes; innate immunity;

    Abstract : Antigenic variation of surface proteins allows microorganisms to evade the immune system of the infected host. This phenomenon represents an apparent paradox, because the variable protein must retain an important function, while its antigenic properties vary extensively. READ MORE

  5. 3. Interactions of human C4BP with Bordetella pertussis and Streptococcus pyogenes

    Author : Karin Berggård; Lund Dermatologi och venereologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; M protein; antigenic variation; phagocytosis resistance; complement; C4b-binding protein C4BP ; Bordetella pertussis; Streptococcus pyogenes; Microbiology; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Abstract : Many microorganisms have developed mechanisms to protect themselves against attack from the complement system of the host. One possible mechanism for a microorganism to evade complement attack is to bind a human complement regulator, which may allow the microorganism to down-regulate complement activation. READ MORE

  6. 4. Antigenic variation in Plasmodium falciparum : understanding the RIFIN protein family

    Author : Nicolas Joannin; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : RIFIN proteins are variable surface antigens, which have a central role in the survival and virulence of the malaria parasite Plasmodium falciparum. Antigenic variation is a mean for these parasites to avoid clearance by the host s immune system. However, this is often a secondary function to the main role of these proteins. READ MORE

  7. 5. Comparative Cell Biology in Diplomonads

    Author : Elin Einarsson; Staffan Svärd; Scott Dawson; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Giardia intestinalis; Spironucleus salmonicida; intestinal parasite; hydrogenosome; encystation; gene regulation; transfection; diplomonad; antigenic variation; annexin;

    Abstract : The diplomonads are a diverse group of eukaryotic flagellates found in microaerophilic and anaerobic environments. The most studied diplomonad is the intestinal parasite Giardia intestinalis, which infects a variety of mammals and cause diarrheal disease. READ MORE