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Showing result 1 - 5 of 40 swedish dissertations matching the above criteria.

  2. 1. Development and Validation of Bioanalytical Methods : Application to Melatonin and Selected Anti-Infective Drugs

    Author : Susanne Römsing; Yngve Bergqvist; Åsa Emmer; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; african trypanosomiasis; melatonin; malaria; antiretroviral drugs; lumefantrine; tafenoquine; lamivudine; nevirapine; zidovudine; sampling paper; dried blood spots; capillary blood; antimalarial drugs; solid-phase extraction; liquid chromatography; Chemistry; Kemi; Analytical Chemistry; Analytisk kemi;

    Abstract : This thesis describes bioanalytical methods for measuring melatonin and some anti-infective drugs in biological fluids. Solid-phase extraction (SPE) or protein precipitation was used for enrichment and purification of the analytes and Liquid Chromatography (LC) was used to analyze the samples. READ MORE

  4. 2. Organometallic complexes with antimalarial properties

    Author : Lotta Glans; Kemisk fysik; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Bioorganometallic chemistry; Chloroquine; Antimalarial; Drug resistance; Organometallic; Arene;

    Abstract : Malaria is a serious disease that causes around 800 000 deaths per year. Current malaria control efforts are hampered by the widespread resistance to common antimalarial drugs, such as the 4-aminoquinoline derivative called chloroquine. READ MORE

  5. 3. Development of Field-adapted Analytical Methods for the Determination of New Antimalarial Drugs in Biological Fluids

    Author : Niklas Lindegårdh; Karin Markides; Yngve Bergqvist; Anders Colmsjö; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Analytical chemistry; LC; liquid chromatography; biological samples; SPE; solid phase extraction; validation; antimalarial drugs; amodiaquine; piperaquine; atovaquone; dried blood spots; Analytisk kemi; Analytical chemistry; Analytisk kemi; Analytical Chemistry; analytisk kemi;

    Abstract : This thesis deals with the development of analytical methods for the determination of new antimalarial drugs in biological fluids. The goal was to develop methods that facilitate clinical studies performed in the field, such as capillary blood sampling onto sampling paper. READ MORE

  6. 4. Development of field-adapted analytical methods for the determination of new antimalarial drugs in biological fluids

    Author : Niklas Lindegårdh; Högskolan Dalarna; []
    Keywords : LC; liquid chromatography; biological samples; SPE; solid phase extraction; validation; antimalarial drugs; amodiaquine; piperaquine; atovaquone; dried blood spots;

    Abstract : .... READ MORE

  7. 5. Development of Analytical Methods for the Determination of Antimalarials in Biological Fluids

    Author : Daniel Blessborn; Yngve Bergqvist; Anders Helander; Högskolan Dalarna; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Malaria; Chloroquine; Quinine; Sulfadoxine; Pyrimethamine; Mefloquine; Lumefantrine; Amodiaquine; Pyronaridine; Proguanil; Atovaquone; Sampling paper; Dried blood spots; Capillary blood; Antimalarial drugs; Solid-phase extraction; Liquid chromatography.; Chemistry;

    Abstract : The aim of this thesis was to develop analytical methods for measuring antimalarial drugs in biological fluids. Solid phase extraction (SPE) was used for the enrichment and purification of the drugs. READ MORE