Search for dissertations about: "antimicrobial peptide"

Showing result 11 - 15 of 128 swedish dissertations containing the words antimicrobial peptide.

  2. 11. Pathogenic Neisseria : Single cell motility, multicellular dynamics and antimicrobial susceptibility

    Author : Olaspers Sara Eriksson; Ann-Beth Jonsson; Matthew Francis; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Neisseria; Type IV pili; Twitching motility; PilT; Microcolony dynamics; PilU; NafA; Antimicrobial peptide; Cell-penetrating peptide; molekylär biovetenskap; Molecular Bioscience;

    Abstract : Neisseria meningitidis and Neisseria gonorrhoeae can colonize humans without causing any symptoms. However, gonorrhea and invasive meningococcal disease are serious health concerns. An essential virulence factor for neisserial adhesion to host cells, twitching motility and microcolony formation/aggregation is the retractile type IV pili (Tfp). READ MORE

  4. 12. Vascular actions of antimicrobial peptides

    Author : Cristina Ciornei; Sektion II; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kardiovaskulära systemet; Cardiovascular system; vascular smooth muscle; sepsis; nitric oxide; human antimicrobial peptide LL-37; Antimicrobial peptides; lipopolysaccharide; bactericidal permeability-increasing protein;

    Abstract : The present thesis focuses on the vascular effects of antimicrobial peptides especially mechanisms involving the vasodilator nitric oxide (NO), which is released from the blood vessel wall during inflammatory conditions such as sepsis. Bacterial lipopolysaccharide stimulates the expression of nitric oxide synthase (iNOS), which increases the NO production in vascular tissues or cultured vascular smooth muscle cells (VSMC). READ MORE

  5. 13. Antimicrobial peptides and virulence factors in meningococcal colonisation and disease

    Author : Miriam Geörg; Ann-Beth Jonsson; Ole E. Sørensen; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Neisseria meningitidis; antimicrobial peptide; LL-37; cell-penetrating peptide; resistance; polynucleotide phosphorylase; molekylär biovetenskap; Molecular Bioscience;

    Abstract : The Gram-negative bacterium Neisseria meningitidis is a transient commensal of the human nasopharynx, but occasionally causes life-threatening disease. During colonisation of its niche, N. meningitidis has to overcome innate immune defences, including the expression of antimicrobial peptides (AMPs). READ MORE

  6. 14. Novel Endogenous Antimicrobial Peptides

    Author : Emma Nordahl; Lund Dermatologi och venereologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; D5; HK; C3a; HMWK; complement; heparin-binding; antibacterial; Antimicrbial peptide; AMP;

    Abstract : Antimicrobial peptides serve as a first line of defence against invading microorganisms and are an essential part of our fast innate immune system. They are ancient molecules found in all classes of life. Antimicrobial peptides rapidly kill a broad spectrum of microbes and are immunomodulatory, i.e. READ MORE

  7. 15. Development of antimicrobial peptides : Methodological aspects, design, synthesis and evaluation of a new class of antimicrobial peptides

    Author : Marie Danielsson; Anders Undén; Maria Kempe; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Abstract : A new protective group for the indole nitrogen of the amino acid tryptophan, the Boc-sarcosinoyl-sarcosinolyl (Boc-Sar-Sar) is described. This protective group shows good stability to the reaction conditions used in solid phase peptide synthesis and can be incorporated into the peptide as Fmoc-Trp(Boc-Sar-Sar)-OH. READ MORE