Search for dissertations about: "antimicrobial potential"

Showing result 1 - 5 of 116 swedish dissertations containing the words antimicrobial potential.

2. 1. Antimicrobial peptides in the treatment of infectious and inflammatory conditions : Preclinical studies of mechanism of action, efficacy, and safety

   Author : Camilla Björn; RISE; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antimicrobial peptides; AMPs; innate immunity; infection; inflammation; mechanism of action; efficacy; safety; antimicrobial resistance; antibiotic resistance; Antimicrobial peptides; AMPs; innate immunity; infection; inflammation; mechanism of action; efficacy; safety; antimicrobial resistance; antibiotic resistance;

   Abstract : The rapid emergence of antibiotic-resistant microbes worldwide and the urgent need of new antimicrobial agents have stimulated interest in antimicrobial peptides (AMPs) as new therapeutics for treatment of infectious diseases. AMPs are present in all living species and constitute an important part of the innate immune system in multicellular organisms, including humans. READ MORE

4. 2. Lipid-based liquid crystals as drug delivery vehicles for antimicrobial peptides

   Author : Lukas Boge; Martin Andersson; Lovisa Ringstad; RISE; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Liquid crystals; liquid crystalline nanoparticles; cubosome; hexosome; phase behavior; antimicrobial peptide; AMP; glycerol monooleate; proteolysis; antimicrobial effect; antimicrobial resistance; bacterial membrane; membrane interaction; infection; topical delivery; pulmonary delivery;

   Abstract : The development of antimicrobial resistance is a great challenge within health sectors worldwide. Thus, demand for new, efficient treatments is urgent in order to treat various bacterial infections. Antimicrobial peptides (AMPs) are a group of antibiotics that have gained more and more attraction in the past decade. READ MORE

5. 3. Antimicrobial potential of Geobacillus sp. ZGt-1 isolated from Zara hot spring in Jordan : Piecing the puzzle of the antagonistic activity of a novel bacterial strain

   Author : Rawana Alkhalili; Bioteknik; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Thermophiles; Geobacillus; antimicrobial potential; antimicrobial peptides; bacteriocins; lanthipeptides; toxin-antitoxin; genome sequence;

   Abstract : The problem of antibiotic resistance is rising continuously, creating a warning signal that calls for finding alternatives. Not only that, but there is also a rising demand for natural food preservatives. The pharmaceutical and food industry sectors are working on fulfilling these needs. This thesis is exploring possible solutions to these issues. READ MORE

6. 4. Vascular actions of antimicrobial peptides

   Author : Cristina Ciornei; Sektion II; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kardiovaskulära systemet; Cardiovascular system; vascular smooth muscle; sepsis; nitric oxide; human antimicrobial peptide LL-37; Antimicrobial peptides; lipopolysaccharide; bactericidal permeability-increasing protein;

   Abstract : The present thesis focuses on the vascular effects of antimicrobial peptides especially mechanisms involving the vasodilator nitric oxide (NO), which is released from the blood vessel wall during inflammatory conditions such as sepsis. Bacterial lipopolysaccharide stimulates the expression of nitric oxide synthase (iNOS), which increases the NO production in vascular tissues or cultured vascular smooth muscle cells (VSMC). READ MORE

7. 5. ANTIMICROBIAL ACTIVITIES OF HISTIDINE-RICH GLYCOPROTEIN AND CATIONIC PEPTIDES

   Author : Victoria Rydengård; Lund Dermatologi och venereologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dermatologi; venereologi; venereology; Dermatology; histidine-rich glycoprotein; heparin-binding; zinc; low pH; Medicine human and vertebrates ; Medicin människa och djur ; innate immunity; antimicrobial;

   Abstract : In an environment full of potential pathogens it is of importance for organisms to mount a fast and effective defence. Antimicrobial peptides are ancient and integral effector molecules of the innate immune system. They are found in all kinds of species from bacteria to plants and animals, indicating their importance during evolution. READ MORE