Search for dissertations about: "antimicrobial"

Showing result 1 - 5 of 333 swedish dissertations containing the word antimicrobial.

  1. 1. Antimicrobial peptides in the treatment of infectious and inflammatory conditions Preclinical studies of mechanism of action, efficacy, and safety

    University dissertation from Göteborgs universitet

    Author : Camilla Björn; Medicinteknik.; Göteborgs universitet.; Gothenburg University.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antimicrobial peptides; AMPs; innate immunity; infection; inflammation; mechanism of action; efficacy; safety; antimicrobial resistance; antibiotic resistance; Antimicrobial peptides;

    Abstract : The rapid emergence of antibiotic-resistant microbes worldwide and the urgent need of new antimicrobial agents have stimulated interest in antimicrobial peptides (AMPs) as new therapeutics for treatment of infectious diseases. AMPs are present in all living species and constitute an important part of the innate immune system in multicellular organisms, including humans. READ MORE

  2. 2. Lipid-based liquid crystals as drug delivery vehicles for antimicrobial peptides

    University dissertation from ; Chalmers tekniska högskola; Gothenburg

    Author : Lukas Boge; [2018]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Liquid crystals; liquid crystalline nanoparticles; cubosome; hexosome; phase behavior; antimicrobial peptide; AMP; glycerol monooleate; proteolysis; antimicrobial effect; antimicrobial resistance; bacterial membrane; membrane interaction; infection; topical delivery; pulmonary delivery;

    Abstract : Många av oss har någon gång blivit tvungna att ta en penicillinkur mot halsfluss eller kanske i samband med någon annan infektion. Oftast har behandlingen varit till stor nytta, och infektioner som förr i tiden kunde leda till döden har varit lätta att behandla med hjälp av antibiotika. READ MORE

  3. 3. Antimicrobial Polymer Composites for Medical Applications

    University dissertation from Stockholm : KTH Royal Institute of Technology

    Author : Peter Kaali; KTH.; [2011]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; medical polymers; antimicrobial; body fluids; degradation; NATURAL SCIENCES Chemistry Organic chemistry Polymer chemistry; NATURVETENSKAP Kemi Organisk kemi Polymerkemi;

    Abstract : The current study and discuss the long-term properties of biomedical polymers in vitro and invivo and presents means to design and manufacture antimicrobial composites. Antimicrobialcomposites with reduced tendency for biofilm formation should lead to lower risk for medicaldevice associated infection. READ MORE

  4. 4. Antimicrobial Peptide Interactions with Phospholipid Membranes Effects of Peptide and Lipid Composition on Membrane Adsorption and Disruption

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Adam A Strömstedt; Uppsala universitet.; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antimicrobial; peptide; adsorption; liposome; membrane; melittin; cholesterol; tryptophan; phospholipid; bilayer; PHARMACY; FARMACI; Pharmaceutical Physical Chemistry; farmaceutisk fysikalisk kemi;

    Abstract : The interactions between antimicrobial peptides and phospholipid membranes were investigated, in terms of lipid headgroup variations and the role of cholesterol, as well as peptide composition and structure. Also strategies for increasing proteolytic stability were evaluated. READ MORE

  5. 5. Functional dualism of antimicrobial host defence peptides

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Åse Björstad; Göteborgs universitet.; Gothenburg University.; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antimicrobial; apoptosis; cathelicidin; host defence peptide; interleukin 8; LL-37; permeabilisation;

    Abstract : Antimicrobial host defence peptides are central to innate immunity and many possess direct antimicrobial actions on bacteria as well as indirect immunomodulatory functions on human leukocytes. Different variants of the bifunctional Helicobacter pylori peptide, Hp(2-20), were synthesised and inhibition zone assays and chemiluminescence systems were employed for determination of direct antimicrobial action and superoxide release (immunomodulatory) from human neutrophils, respectively. READ MORE