Search for dissertations about: "antiobesity thesis"

Found 5 swedish dissertations containing the words antiobesity thesis.

  2. 1. Insulin-like Growth Factor-I (IGF-I) and Interleukin-6 (IL-6) regulate body fat

    Author : Kristina Wallenius; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obesity; insulin-like growth factor I IGF-I ; interleukin-6 IL-6 ; growth hormone GH ; GH releasing factor GHRF ; GH secretagogue GHS ; receptor; leptin; insulin; glucose; intracerebroventricular ICV ; dual-energy X-ray absorptiometry DXA ; indirect calorimetry.;

    Abstract : The aim of this thesis was to investigate the role of insulin-like growth factor-I (IGF-I) and interleukin-6 (IL-6) in the regulation of metabolism and body fat mass. Circulating IGF-I is mainly liver derived, while a large part of circulating IL-6 is produced by adipose tissue. READ MORE

  4. 2. Conjugated linoleic acid and the metabolic syndrome : Clinical and metabolic studies with special reference to insulin resistance, oxidative stress and inflammation

    Author : Ulf Risérus; Keith Frayn; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Metabolic syndrome; dietary fatty acids; conjugated linoleic acid; insulin resistance; oxidative stress; inflammation; cardiovascular disease; dyslipidemia; abdominal obesity; type 2 diabetes; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; Nutrition; näringslära;

    Abstract : The aim of this thesis was to investigate the metabolic effects of conjugated linoleic acid (CLA) in middle-aged men with the metabolic syndrome, a high-risk group for type 2 diabetes. CLA is a group of fatty acid isomers with antiobesity and antidiabetogenic effects in animals, and CLA is therefore used as a supplement in humans. READ MORE

  5. 3. Angiogenesis in obesity and cancer

    Author : Ebba Bråkenhielm; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Adiponectin; endothelial cells; Leptin; Resveratrol; TNP-470;

    Abstract : Angiogenesis is the process of blood vessel growth from pre-existing vasculatures. In the adult, it is involved in certain physiological processes, such as in organ and tissue regeneration, wound healing, and in female reproductive cycles. READ MORE

  6. 4. Classification, Evolution, Pharmacology and Structure of G protein-coupled Receptors

    Author : Malin C Lagerström; Helgi B. Schiöth; Robert Fredriksson; Anthony J. Harmar; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacology; Classification; Structure; Pharmacology; Evolution; G protein-coupled receptor; Farmakologi; Pharmacological research; Farmakologisk forskning;

    Abstract : G protein-coupled receptors (GPCR) are integral membrane proteins with seven α-helices that translate a remarkable diversity of signals into cellular responses. The superfamily of GPCRs is among the largest and most diverse protein families in vertebrates. READ MORE

  7. 5. Severe childhood obesity : behavioural and pharmacological treatment

    Author : Pernilla Danielsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: Childhood obesity is a chronic disease associated with increased morbidity, psychosocial problems and reduced life expectancy, all of which is today very common. Despite this, long-term studies of behavioural treatment of childhood obesity are currently lacking. READ MORE