Search for dissertations about: "antipsychotics"

Showing result 16 - 20 of 42 swedish dissertations containing the word antipsychotics.

  2. 16. Electrophysiology-based investigations of G protein-coupled receptor pharmacology

    Author : Richard Ågren; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : G protein-coupled receptors (GPCRs) constitute targets for ~34% of approved drugs. The muscarinic acetylcholine M2 receptor (M2R) activates G protein-coupled receptor inward rectifying potassium (GIRK) channels in the central nervous system and heart. Membrane potential modulates agonist potency at several GPCRs. READ MORE

  4. 17. Psychotropic and analgesic drug use among old people : with special focus on people living in institutional geriatric care

    Author : Hugo Lövheim; Yngve Gustafson; Stig Karlsson; Lars-Olof Wahlund; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dementia; depression; pain; nursing Home; old; analgesics; antidepressants; anti-psychotics; behavioral and psychological symptoms of dementia; inappropriate drugs; Geriatrics and medical gerontology; Geriatrik och medicinsk gerontologi;

    Abstract : Old people in general, and those affected by dementia disorders in particular, are more sensitive to drug side effects than younger people. Despite this, the use of nervous system drugs and analgesics among old people is common, and has increased in recent years. READ MORE

  5. 18. Psychotropic drug treatment during pregnancy and lactation : effects on mother and child

    Author : Essi Whaites Heinonen; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The common major depressive disorder and anxiety disorders are often treated with antidepressants. Treatment with mood-stabilizers and antipsychotics are important for pregnant women with bipolar and psychotic disorders, as these women are at risk of postpartum psychosis and even suicide if not treated. READ MORE

  6. 19. Hazards of Drug Therapy : On the Management of Adverse Drug Reactions: From Signal Detection and Evaluation to Risk Minimization

    Author : Karin Hedenmalm; Marja-Liisa Dahl; Gunnar Alvan; Ellen Vinge; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacology; adverse drug reactions; spontaneous reporting systems; drug regulation; pharmacovigilance; incidence; Farmakologi; Pharmacological research; Farmakologisk forskning;

    Abstract : Spontaneous reporting systems (SRSs) for adverse drug reactions (ADRs) have been developed as a result of the thalidomide disaster, whereby thousands of children world-wide were born with birth defects. The Swedish Adverse Drug Reactions Advisory Committee was established in 1965. READ MORE

  7. 20. Regulation of signal transduction in the striatum by typical and atypical antipsychotic drugs

    Author : Kerstin Håkansson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Adenosine A2A receptor; basal ganglia; cAMP-dependent protein kinase; clozapine; DARPP-32; dopamine D 2 receptor; extracellular signal-regulated protein kinases 1 and 2; extrapyramidal side effects; glutamate AMPA receptor; haloperidol; knockout mouse; phosphorylation; schizophrenia; tyrosine hydroxylase.;

    Abstract : The only effective therapy for schizophrenia is based on the use of antipsychotic drugs. These substances act as dopamine D 2 receptor antagonists and can be classified as typical or atypical. Typical antipsychotics, e.g. READ MORE