Search for dissertations about: "antiretroviral treatment"

Showing result 1 - 5 of 116 swedish dissertations containing the words antiretroviral treatment.

  1. 1. Antiretroviral treatment of HIV-1 in the central nervous system

    Author : Aylin Yilmaz; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : HIV-1; cerebrospinal fluid; antiretroviral treatment; lopinavir; saquinavir; nelfinavir; neopterin; beta-2-microglobulin; HIV-1 RNA; IgG index; blood-brain barrier; albumin ratio; ultra-ultra sensitive PCR;

    Abstract : HIV-1 invades the central nervous system (CNS) early in the infectious course. It establishes a chronic progressive infection, and triggers an intrathecal immune response. If left untreated, a majority of patients will develop neurological complications, caused by opportunistic pathogens or HIV-1 itself. READ MORE

  2. 2. Pharmacometric Models to Improve Treatment of Tuberculosis

    Author : Elin M Svensson; Mats O Karlsson; Maria C Kjellsson; Ulrika S H Simonsson; N. L’Ntshotsholé (Shasha) Jumbe; Uppsala universitet; []
    Keywords : pharmacokinetics; pharmacodynamics; population approach; nonlinear mixed-effects models; multidrug-resistant tuberculosis; bedaquiline; antiretroviral; drug-drug interactions; time-to-event; albumin; Klinisk farmakologi; Clinical Pharmacology;

    Abstract : Tuberculosis (TB) is the world’s most deadly infectious disease and causes enormous public health problems. The comorbidity with HIV and the rise of multidrug-resistant TB strains impede successful therapy through drug-drug interactions and the lack of efficient second-line treatments. READ MORE

  3. 3. Adherence and Readiness to Antiretroviral Treatment

    Author : Björn Södergård; Åsa Kettis Lindblad; Mary P Tully; Anders Sönnerborg; Marja Airaksinen; Uppsala universitet; []
    Keywords : Community pharmacy services; Adherence; Readiness; HIV; Pharmacy; Samhällsfarmaci;

    Abstract : Antiretroviral therapy places extraordinarily high demands on adherence, since non-adherence affects both individuals and society due to the spread of resistant viral strains. The aims of the thesis were to investigate the prevalence of adherence in Swedish HIV-infected patients, changes in adherence over time, and factors associated with adherence, including patients’ readiness to adhere. READ MORE

  4. 4. Antiretroviral Treatment at Ethiopian Health Centers

    Author : Anton Reepalu; Klinisk infektionsmedicin; []

    Abstract : In 2017,for the first time, more than half of all people living with HIV (PLHIV) had access to antiretroviral treatment (ART). This expansion of ART has in part been achieved through decentralization of HIV care in resource-limited settings. There, many PLHIV now receive care at ART clinics integrated within the primary health care system. READ MORE

  5. 5. HIV-1 infection of the central nervous system. Markers of pathogenesis and antiretroviral treatment effects

    Author : Sahra Abdulle; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : HIV-1; cerebrospinal fluid; antiretroviral therapy; neopterin; beta2-microglobulin; CSF HIV-1 RNA; blood-brain barrier; IgG index; HIV-related neurological diseases; AIDS Dementia Complex; neurofilament protein; HIV-1 genetic subtypes;

    Abstract : Human immunodeficiency virus type 1 (HIV-1) invades the central nervous system (CNS) early in the course of infection and either directly or through opportunistic infections causes a spectrum of neurological complications. The most severe manifestation of HIV-1 CNS infection is AIDS Dementia Complex (ADC), which occurs in approximately 20% of untreated patients with AIDS. READ MORE