Search for dissertations about: "ap"

Showing result 1 - 5 of 289 swedish dissertations containing the word ap.

  2. 1. Transcription Factor AP-2 in Relation to Personality and Antidepressant Drugs

    Author : Cecilia Berggård; Lars Oreland; Göran Engberg; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacology; Transcription factors; serotonin; AP-2; antidepressants; CNS; personality; Farmakologi; Pharmacological research; Farmakologisk forskning;

    Abstract : The CNS monoaminergic systems are considered as the head engine regulating neuropsychiatric functions and personality. Transcription factor AP-2 is known to be essential for the development of the brainstem including the monoaminergic nuclei, and has the ability to regulate many genes in the monoaminergic systems. READ MORE

  4. 2. Studies of penta-decameric binding proteins: AP-4 and CBF-A

    Author : Alaitz Aranburu; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; transplantation; Metabolism; serologi; metabolism; Biokemi; serology; Immunology; hnRNP H; NPM; CBF-A; AP-4; transcription; B cells; immunoglobulin; Immunologi;

    Abstract : Each immunoglobulin (Ig) V gene segment contains an upstream promoter region. The octamer element and the TATA box are the only elements that are conserved in all Ig promoters. The presence of the octamer element is necessary, but not sufficient to support high levels of transcription. READ MORE

  5. 3. Transcription Factor AP-2 in Relation to Serotonergic Functions in the Central Nervous System

    Author : Mattias Damberg; Elias Eriksson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacology; CNS; serotonin; transcription factors; AP-2; personality; antidepressants; Farmakologi; Pharmacological research; Farmakologisk forskning; medicinsk farmakologi; Medical Pharmacology;

    Abstract : Eukaryotic gene transcription plays a regulatory role in mammalian developmental processes. It has been shown that transcriptional control is an important mechanism for specification of neurotransmitter phenotypes. READ MORE

  6. 4. Macrophage Activation and AP-1 in Atherosclerosis

    Author : Maria Stollenwerk; Kardiovaskulär forskning - immunitet och ateroskleros; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kardiovaskulära systemet; Proteins; enzymology; Proteiner; enzymologi; Cardiovascular system; carotid plaque; interleukin-1b; caspase-1.; very low-density lipoprotein; fatty acids; activator protein-1; inflammation; Atherosclerosis; nuclear factor-kB; macrophages; tumor necrosis factor;

    Abstract : High levels of very low density lipoprotein (VLDL) and intermediate density lipoprotein (IDL) have been identified as independent risk factors for coronary heart disease. Hypertriglyceridemia is generally associated with an increased expression of inflammatory makers and inflammation is thought to contribute to atherosclerosis and its complications. READ MORE

  7. 5. Assessing carotid plaque structure

    Author : Isabel Goncalves; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiovascular system; Kardiovaskulära systemet; Modified LDL; Antibodies; Lipids; AP-1; Cellularity; Extracellular Matrix; Calcification; Elastin; Stroke; Gray-Scale Median; Echogenicity; Ultrasound; Atherosclerosis; Carotid Plaque;

    Abstract : Atherosclerosis is the leading cause of death and disability in the western world. Its clinical complications include acute myocardial infarction, sudden death and stroke. Thirty to 40 % of all ischemic strokes are caused by a carotid stenosis. READ MORE