Search for dissertations about: "apoA-I"

Showing result 1 - 5 of 13 swedish dissertations containing the word apoA-I.

  2. 1. Structural studies of HDL and applications of EM on membrane proteins

    Author : Lin Zhu; Hans Hebert; Caroline Jegerschöld; Catherine Vénien-Bryan; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; high density lipoprotein; rHDL; apoA-I; transmission electron microscopy; membrane protein; nanodisc; Salipro; transporter; Technology and Health; Teknik och hälsa;

    Abstract : A large number of proteins interact with biological membranes, either integrated in the membrane (PepTSo2), embedded on a membrane surface (5-lipoxygenase) or encircling a cutout of lipid bilayer (apolipoprotein1 (apoA-I). They function as transporters, receptors or biocatalysts in cellular processes like inflammation or cholesterol transport which are touched upon here. READ MORE

  4. 2. Apolipoprotein A-I in glucose metabolism and amyloidosis

    Author : Oktawia Nilsson; Medicinsk proteinvetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Amyloidosis; Apolipoprotein A-I; beta cell; cardiovascular disease; cholesterol efflux; diabetes; glucose metabolism; glycation; high-density lipoprotein; insulin secretion;

    Abstract : The role of Apolipoprotein A-I (ApoA-I), the main protein component of HDL, in cholesterol transport and metabolism is well known and has been studied for more than four decades. More recently, ApoA-I protein has been shown to also have a positive role in glucose control by both stimulation of glucose uptake by muscles and by increasing glucose-stimulated pancreatic insulin secretion. READ MORE

  5. 3. Protein and lipid interactions of mammalian antibacterial peptides

    Author : Yuqin Wang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Gene-encoded antibacterial peptides are multifunctional effector molecules and play an important role in host innate immunity. Upon stimulation, the mature active peptides are released from inactive precursors. READ MORE

  6. 4. Atherosclerosis in middle-aged men. A prospective study with focus on factors related to the metabolic syndrome

    Author : Karin Wallenfeldt; Göteborgs universitet; []
    Keywords : apolipoproteins; atherosclerosis; C-reactive protein; insulin resistance; intima-media thickness; LDL cholesterol; longitudinal study; metabolic syndrome X; smokeless tobacco; ultrasonography;

    Abstract : The metabolic syndrome (MetS) is a clustering of cardiovascular disease CVD) risk factors. Pro-spective studies have demonstrated that patients with MetS are about three times more likely to experience CVD events than those without MetS. Up to one third of the adult population seems to be affected worldwide. READ MORE

  7. 5. Co-assembly of proteins and lipids : From lipodiscs to amyloid aggregates

    Author : Rebecca Frankel Willén; NanoLund: Centre for Nanoscience; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; amyloid; Aβ42; apolipoprotein A-1; aggregation; high-density lipoprotein; DNAJB6; Alzheimer s disease; protein-lipid interactions;

    Abstract : Assemblies of different molecules is a prevalent phenomenon in nature, and crucial in biological life. Most of the biological assemblies are co-assembledcomposites, made up from several different components, either of thesame biomolecular type or a combination of different ones. READ MORE