Search for dissertations about: "apolipoprotein B"

Showing result 1 - 5 of 67 swedish dissertations containing the words apolipoprotein B.

  1. 1. Studies on the assembly and secretion of apolipoprotein B containing lipoproteins

    Author : Karin Lindberg; Göteborgs universitet; []
    Keywords : apolipoprotein B; lipoprotein; lipoprotein biosynthesis; Brefeldin A; microsomal triglyceride transfer protein; liver fatty acid binding protein;

    Abstract : Lipoproteins are water-soluble particles of lipids and proteins, which deliver water-insoluble lipids from intestine or liver to target tissues where the lipids are used as fuel or storage. Lipoproteins consist of a core of hydrophobic lipids surrounded by an amphipatic monolayer of polar lipids and specific proteins, apolipoproteins. READ MORE

  2. 2. Peripheral apolipoprotein E and its emerging role in neurodegenerative disease

    Author : Andreas Giannisis; Henrietta M. Nielsen; Kim Kultima; Johan Ankarklev; Cheryl Wellington; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer’s disease; apolipoprotein E; humanized-liver mice; race; diet; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Abstract : The human apolipoprotein E gene (APOE) is polymorphic and coding for three common alleles; ε2, ε3, and ε4. Carriers of the ε4 allele are at a higher risk of developing sporadic late-onset Alzheimer’s Disease (AD). This association appears to be influenced by inherited traits, race, and sex. READ MORE

  3. 3. Retention of atherogenic lipoproteins in atherogenesis

    Author : Maria Gustafsson; Göteborgs universitet; []
    Keywords : apolipoprotein B; atherosclerosis; LDL; LpL; proteoglycans; retention; sPLA2;

    Abstract : Atherosclerosis is the most common cause of death in the industrialized world. The diseaseis characterized by lipid accumulation and inflammation in the arterial wall, which may leadto obstruction of the blood flow. READ MORE

  4. 4. Atherogenic lipoproteins and their interaction with proteoglycans

    Author : Christofer Flood; Göteborgs universitet; []
    Keywords : apolipoprotein B; atherosclerosis; LDL; proteoglycan; sPLA2; ; retention;

    Abstract : Atherosclerosis is a multi-factorial disease and its pathogenesis is still unclear. However, accumulating evidence during recent years has led to the concept that subendothelial retention of atherogenic lipoproteins is the initiating event in atherogenesis. READ MORE

  5. 5. Myocardial creatine metabolism in experimental infarction and heart failure

    Author : Malin Lindbom; Göteborgs universitet; []
    Keywords : Energy metabolism; Creatine; Congestive heart failure; Myocardial infarction; Ventricular arrhythmias; Cardiac remodeling; apolipoprotein B; Lipid metabolism;

    Abstract : The failing heart is characterized by changes in structure, function and metabolism. All these changes are usually defined as pathologic remodelling. An important part of this negative remodelling process is disturbances in the myocardial energy metabolism. READ MORE