Search for dissertations about: "apolipoprotein B"

Showing result 11 - 15 of 67 swedish dissertations containing the words apolipoprotein B.

  1. 11. Apolipoprotein A-IV and Transthyretin in Swedish Forms of Systemic Amyloidosis

    Author : Joakim Bergström; Per Westermark; Giampaolo Merlini; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; Amyloid; Fibril; Aggregation; Apolipoprotein A-IV; Transthyretin; Seeding; Senile systemic amyloidosis; Familial amyloidotic polyneuropathy; Patologi; Pathology; Patologi;

    Abstract : Over 20 different plasma proteins have been shown to have the capacity to undergo conformational changes and self-assemble into highly stable and insoluble amyloid fibrils. One, transthyretin (TTR), consists of 127 amino acid residues arranged in eight β-strands (named A to H) and is involved in two different clinical forms of amyloidosis. READ MORE

  2. 12. Assembly and Secretion of Atherogenic Lipoproteins

    Author : Caroline Beck; Göteborgs universitet; []
    Keywords : very low-density lipoprotein; ; apolipoprotein B100; ; B-cell receptor associated; microsomal triglyceride transfer protein; ; secretion; assembly;

    Abstract : The classical dyslipidemia seen in patients with type 2 diabetes is characterized by elevated serum triglycerides (TG), low levels of high-density lipoprotein cholesterol and the appearance of small, dense low-density lipoproteins (LDL). It is now recognized that the different components of diabetic dyslipidemia are not isolated abnormalities but are closely linked to each other metabolically, and are initiated by the hepatic overproduction of large triglyceride-rich very low-density lipoproteins (VLDL1). READ MORE

  3. 13. Tissue Repair Responses and Integrity of the Atherosclerotic Plaque

    Author : Sabrina Hsiung; Kärlväggsbiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; atherosclerosis; diabetes; tissue repair; plaque; interleukin-22; cardiovascular disease; apolipoprotein B-100; shear stress;

    Abstract : .... READ MORE

  4. 14. Development of a Passive Immunization Strategy Against Atherosclerosis

    Author : Alexandru Schiopu; Kardiovaskulär forskning - immunitet och ateroskleros; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; regression; plaque; peptide; oxidized LDL; immune system; carotid stenosis; cardiovascular diseases; apolipoprotein B-100; atherosclerosis; Kardiovaskulära systemet; Cardiovascular system; vascular injury; ultrasound; antibodies;

    Abstract : Atherosclerosis is a chronic inflammatory disease, characterized by the accumulation of lipids and fibrous tissue in the wall of medium and large-sized arteries. The characteristic culprit of the disease is the atheroma, or atherosclerotic plaque, a patchy thickening of the arterial wall which affects the lumen, inducing various degrees of stenosis. READ MORE

  5. 15. Novel Biomarkers and Immunomodulating Therapies Targeting Cardiovascular Diseases

    Author : Ingrid Yao Mattisson; Kardiovaskulär forskning - immunitet och ateroskleros; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Atherosclerosis; apolipoprotein B-100; cardiovascular disease CVD ; autoimmunity; systemic lupus erythematosus; Inflammation;

    Abstract : .... READ MORE