Search for dissertations about: "apolipoprotein J"
Found 5 swedish dissertations containing the words apolipoprotein J.
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1. Hepatic lipase and dolichol esterification
Abstract : Dolichol is one of the mevalonate pathway end products, present in all tissues and cellular membranes. The lipid is a primary alcohol consisting of 16-23 isoprenoid residues and occurs as a free alcohol, monophosphate or fatty acyl ester. READ MORE
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2. Prediction Models and Pharmacogenomics in Adult Growth Hormone Deficiency
Abstract : The overall aim of this thesis was to study clinical and genetic factors that influence response to growth hormone replacement therapy (GHRT) in GH deficient (GHD) adults. The patients were part of a cohort of adults with hypopituitarism and severe GHD who were studied before and after 12 months of GHRT. READ MORE
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3. Clusterin in brain and cerebrospinal fluidin Alzheimer s disease
Abstract : The apolipoprotein clusterin is suggested to be involved in the pathogenesis of Alzheimer¡¦s disease (AD). At the start of these studies, results had indicated that clusterin was elevated in AD brain, compared with controls. READ MORE
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4. Apolipoprotein CIII in the pathophysiology of diabetes mellitus
Abstract : It has previously been shown that high levels of apolipoprotein CIII (apoCIII) are related to both type-1 (T1D) and type-2 diabetes (T2D). In this thesis, mechanisms whereby apoCIII affects diet- and genetically-induced obesity and metabolic derangements, and the role of the environment and apoCIII in the development of T1D, have been studied. READ MORE
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5. Computational Protein Evolution : Modeling the Selectivity and Promiscuity of Engineered Enzymes
Abstract : Enzymes are biological catalysts that significantly increase the rate of all biochemical reactions that take place within cells and are essential to maintain life. Many questions regarding their function remain unknown. READ MORE