Search for dissertations about: "apolipoprotein-E cognition"

Showing result 1 - 5 of 7 swedish dissertations containing the words apolipoprotein-E cognition.

  1. 1. Peripheral apolipoprotein E and its emerging role in neurodegenerative disease

    Author : Andreas Giannisis; Henrietta M. Nielsen; Kim Kultima; Johan Ankarklev; Cheryl Wellington; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer’s disease; apolipoprotein E; humanized-liver mice; race; diet; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Abstract : The human apolipoprotein E gene (APOE) is polymorphic and coding for three common alleles; ε2, ε3, and ε4. Carriers of the ε4 allele are at a higher risk of developing sporadic late-onset Alzheimer’s Disease (AD). This association appears to be influenced by inherited traits, race, and sex. READ MORE

  2. 2. Mild head injury : Relation to cognition, dementia, fatigue & genetics

    Author : Anna Sundström; Lars Nyberg; Maria Levander; Umeå universitet; []
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Neuropsychology; mild head injury; mild brain injury; apolipoprotein E; Psychology; Psykologi;

    Abstract : Following a mild head injury (MHI), a person may report a variety of symptoms such as headache, memory disturbance, dizziness, and concentration difficulties. For most persons the symptoms are transient, but some suffer persistent symptoms that can have a major impact on everyday life. READ MORE

  3. 3. The effects of Nordic berries on cognition and brain function : Connections with gut microbiota composition and cardiometabolic risk markers

    Author : Fang Huang; Bioteknik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Nordic berries; cognition; brain function; gut microbiota; cardiometabolic function;

    Abstract : An aging population is associated with an increased prevalence of cognitive decline and related diseases. Gradual cognitive decline is a natural feature of aging, but may also develop into a more severe loss of cognitive function, manifesting as mild cognitive impairment or severe cognitive disease. READ MORE

  4. 4. Telomeres and the brain : an investigation into the relationships of leukocyte telomere length with functional and structural attributes of the brain

    Author : Mikael Wikgren; Karl-Fredrik Norrback; Rolf Adolfsson; Göran Roos; Thomas Karlsson; Brenda Penninx; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; APOE; aging; atrophy; brain; cognition; cortisol; depression; hippocampus; HPA axis; MRI; stress; telomere length; white matter hyper-intensities.;

    Abstract : Telomeres are the outermost parts of linear chromosomes. They consist of tandemly repeated non-coding short nucleotide sequences (TTAGGG in all vertebrates), in humans spanning over the last 2 to 15 kilobase pairs of the chromosome. Due to the end-replication problem, telomeres shorten with each cellular division. READ MORE

  5. 5. Cognitive functioning in the preclinical stages of Alzheimer's disease and vascular dementia

    Author : Sari Jones; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Cognition; preclinical; Alzheimer s disease; vascular dementia; neuropsychology;

    Abstract : This doctoral thesis concerns cognitive functioning in the preclinical stages of Alzheimer's disease (AD) and vascular dementia (VaD). It is based on five empirical studies using data from the Kungsholmen Project, a longitudinal population-based study of aging and dementia targeting persons 75 years and older, living in the Kungsholmen District in Stockholm, Sweden. READ MORE