Search for dissertations about: "apoptosis TNF"

Showing result 11 - 15 of 80 swedish dissertations containing the words apoptosis TNF.

2. 11. Macrophage-material surface interactions

   Author : Christina Gretzer; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Apoptosis; biomaterials; cell-cell interactions; cell-material interactions; cytokines; differentiation; fibrinogen; hydrogen peroxide; LPS; monocytes; particles;

   Abstract : Material surface-stimulated activation of the macrophage and the release of mediators has been suggested to be an important factor for inflammation and tissue regeneration around biomedical implants. Macrophage interactions with particles released from implants as well as macophage-bacteria interactions are also involved in implant loosening processes. READ MORE

4. 12. Mechanisms of neutrophil recruitment in septic lung injury

   Author : Karzan Palani; Kirurgi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; sepsis; infection; neutrophil; lung; chemokines; apoptosis; CD44; F-actin; peptides;

   Abstract : Sepsis is one of leading cause of death despite aggressive surgical intervention and antibiotic therapies. Excessive neutrophil recruitment is a major feature in early phase with immune system dysfunction at later phase. Lung is the most vulnerable, critical and sensitive organ during sepsis process. READ MORE

5. 13. Mechanisms of Interferon-α Induction in Systemic Lupus Erythematosus

   Author : Ullvi Båve; Lars Rönnblom; Gunnar V. Alm; Ingrid Lundberg; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Systemic lupus erythematosus; interferon inducer; apoptosis; autoantibodies; natural interferon-alpha producing cell; FcgammaRII; Sjögren´s syndrome; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; Medicine; medicin;

   Abstract : Patients with systemic lupus erythematosus (SLE) have an activated type I interferon (IFN) system with an ongoing IFN-α synthesis. This may be caused by circulating immune complexes, consisting of anti-DNA antibodies (Abs) and DNA, with IFN-α inducing capacity. READ MORE

6. 14. Studies of the pathogenesis of hemolytic uremic syndrome and thrombotic thrombocytopenic purpura

   Author : Diana Karpman; Lund Pediatrik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pediatri; Pediatrics; tumor necrosis factor; interleukin 6; von Willebrand factor; apoptosis; lipopolysaccharide; shiga-like toxin; Escherichia coli O157:H7; Hemolytic uremic syndrome; thrombotic thrombocytopenic purpura; Urology; nephrology; Urologi; nefrologi;

   Abstract : This study investigated the pathogenesis of hemolytic uremic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP). (1) The relative roles of lipopolysaccharide and Shiga-like toxin-2 were studied in a mouse model of Escherichia coli O157:H7 infection. READ MORE

7. 15. Apoptosis in chronic inflammation, with specific reference to airway disease

   Author : Malin Müller; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Apoptosis; asthma; chronic inflammation; lung; sarcoidosis; tributyltin TBT ;

   Abstract : Mechanisms governing the normal resolution processes of inflammation in the lung are poorly understood, yet their elucidation may lead to a greater understanding of the pathogenesis of several pulmonary inflammatory disorders. The elimination of activated lymphocytes by apoptosis is one prerequisite for resolution, and knowledge concerning the role of apoptosis in chronic inflammation is still far from complete. READ MORE