Search for dissertations about: "apoptosis TNF"
Showing result 6 - 10 of 80 swedish dissertations containing the words apoptosis TNF.
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6. Microbe-induced apoptosis in phagocytic cells and its role in innate immunity
Abstract : Apoptosis, or programmed cell death, is a controlled process by which aged or damages cells are eliminated in multicellular organisms. Neutrophils, short-lived phagocytes of the innate immune system, are highly equipped effectors that can sense, locate, ingest and kill bacterial pathogens. READ MORE
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7. Host cell responses to Helicobacter pylori secreted factors
Abstract : The infection of the human gastric mucosa by the bacterium Helicobacter pylori can lead to the development of gastritis, gastroduodenal ulcers, and cancer. The factors that determine disease development in a small percentage of infected individuals are still not fully understood. READ MORE
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8. Cyclin A1 Expression and Regulation in Hematopoietic and Leukemic Cells
Abstract : Increased expression of the cell cycle regulatory protein cyclin A1 has previously been detected in patients with acute myeloid leukemia (AML) and targeted overexpression of cyclin A1 in a transgenic mouse model initiated AML. The aim of this thesis was to further study the expression and regulation of cyclin A1 in hematopoietic cells. READ MORE
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9. Novel Roles of the Ack1 Kinase in Epithelial Biology
Abstract : Epithelial homeostasis is maintained through integration of diverse signals that regulate cell fate. A strict control of such signals is required to prevent overproliferation and, ultimately, oncogenesis. In this thesis we identify novel roles of Activated Cdc42-associated kinase 1 (Ack1) in maintenance of epithelial homeostasis. READ MORE
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10. Tissue Factor regulation, signaling and functions beyond coagulation with a focus on diabetes
Abstract : Background: Tissue factor (TF) is a 47 kDa transmembrane glycoprotein best known for initiating the coagulation cascade upon binding of its ligand FVIIa. Apart from its physiological role in coagulation, TF and TF/FVIIa signaling has proved to be involved in diseases such as diabetes, cancer and cardiovascular diseases. READ MORE