Search for dissertations about: "aquaglyceroporin"

Showing result 1 - 5 of 8 swedish dissertations containing the word aquaglyceroporin.

  1. 1. Tethered Lipid Vesicles as Nanoscale Sensor Elements

    Author : Seyed Tabaei; Chalmers University of Technology; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; aquaglyceroporin; lipid vesicles; total internal reflection fluorescence TIRF microscopy; cell membrane; aquaporin; pore formation; surface plasmon resonance SPR ; phospholipase A2; antiviral peptide; lipid bilayer; biosensing; microfluidics;

    Abstract : The primary aim of this thesis work has been to explore and advance the potential of surface tethered lipid vesicles as a platform for studying in particular the following three biomembrane-related processes: trans-membrane transport, membrane-peptide interactions and the activity of membrane active enzymes. First, a method based on surface plasmon resonance (SPR) spectroscopy was developed for studying passive diffusion processes as well as the membrane-protein mediated transport of small non electrolyte molecules across lipid bilayers. READ MORE

  2. 2. Regulation of glycerol efflux in adipocytes. Structural and functional studies of the glycerol channel aquaporin 7

    Author : Sofia de Mare; Medicinsk strukturbiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glycerol : metabolism; Lipolysis; X-ray Crystallography; Perilipin 1; Aquaglyceroporin; Aquaporin 7; Adipocytes metabolism; Glycerol : metabolism; adipocyte metabolism; X-ray crystallography; Aquaglyceroporin; Aquaporin 7; Perilipin 1; Lipolysis;

    Abstract : Glycerol levels in adipocytes depend on the lipolysis, the hydrolysis of triglycerides into glycerol and free fatty acids, and the efflux of glycerol across the plasma membrane through glycerol channels. The aims of this work were to investigate how glycerol levels are regulated on a molecular level by PLIN1, a major lipid droplet-associated protein and a key regulator of the lipolysis by scaffolding for lipolytic proteins on the lipid droplet. READ MORE

  3. 3. Plant major intrinsic proteins. Identification and characterization of novel water channel-like protiens

    Author : Sofia Gustavsson; Biokemi och Strukturbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Växtbiokemi; Plant biochemistry; GIP; SIP; GUS; immunolabelling; aquaporin; aquaglyceroporin;

    Abstract : The Major Intrinsic Proteins, MIPs, constitute a large, ancient superfamily of membrane proteins that are found in all kingdoms of life. Most MIPs facilitate passive diffusion of water across biological membranes (aquaporins), although many channels are also permeable for glycerol and other small uncharged solutes, (aquaglyceroporins). READ MORE

  4. 4. Functional characterisation of the yeast aquaglyceroporin Fpsl

    Author : Caroline Filipsson; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : ;

    Abstract : .... READ MORE

  5. 5. Development of Surface-Based Methods for Studies of Non-Electrolyte Membrane Transport

    Author : Seyed Tabaei; Chalmers University of Technology; []
    Keywords : membrane junction; surface plasmon resonance; membrane transfer; supported lipid bilayer; quartz crystal microbalance; aquaporin; bicelles; fluorescence microscopy;

    Abstract : Membrane-transport proteins are a diverse family of proteins that all span the cell membrane where they control the transfer of nutrients, metabolites and ions into and out of the cell. Due to their vital role for the function of cells, reliable methods, preferably with high-throughput capacity, to study this class of proteins are essential in fundamental studies as well as in discovery and development of new drugs. READ MORE