Search for dissertations about: "articular chondrocytes"

Showing result 1 - 5 of 33 swedish dissertations containing the words articular chondrocytes.

  2. 1. Production of neocartilage tissues using primary chondrocytes

    Author : Janne Ylärinne; Mikko Lammi; Chengjuan Qu; Mats Brittberg; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; primary chondrocytes; articular cartilage; tissue engineering; neocartilage; scaffold; scaffold-free; hyaluronan; self-assembling peptide; TGF-β3; glucosamine sulfate; hypoxia; hypertonic medium; glucose;

    Abstract : Hyaline cartilage is a highly specialized tissue, which plays an important role in the articulating joints of an individual. It provides the joints with a nearly frictionless, impact resisting surface to protect the ends of the articulating bones. READ MORE

  4. 2. Human articular chondrocytes. Plasticity and differentiation potentials

    Author : Tommi Tallheden; Göteborgs universitet; []
    Keywords : autologous chondrocyte transplantation; dedifferentiation; redifferentiation; stem; cells;

    Abstract : Articular cartilage has no or very low ability for self-repair and untreated lesions may lead tothe development of Osteoarthritis (OA). One method, which has been proved to result in longterm repair of isolated lesions, is autologous chondrocyte transplantation (ACT). READ MORE

  5. 3. Articular cartilage proteoglycan biosynthesis and sulfation

    Author : Chengjuan Qu; Mikko Lammi; Heikki Helminen; Juha Töyräs; Anna-Marja Säämänen; Finland Kuopio University of Kuopio Anatomy Department of Biomedicine; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Cartilage; Chondrocytes metabolism; Chondroitin sulfates; Glycosaminoglycans; Osteoarthritis; Proteoglycans; Glucosamine; Sulfation; Biochemistry; biokemi; cellforskning; cell research; Orthopaedics; ortopedi;

    Abstract : Glucosamine (GlcN) and glucosamine sulfate (GS) have been used to treat the patients with osteoarthritis(OA) as a disease-modifying agent. Previousin vitro studies have focused on the effects of GlcN or GSon cartilage metabolism, whereas in vivo studies have investigated their potential for the treatment of OA. READ MORE

  6. 4. Influences of in vivo and in vitro loading on the proteoglycan synthesis of articular cartilage chondrocytes

    Author : Mikko Lammi; Markku Tammi; Jukka Finne; Tim Hardingham; Finland Kuopio University of Kuopio Department of Anatomy; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Articular cartilage; proteoglycans; loading; stress; hydrostatic pressure; biokemi; Biochemistry; cell research; cellforskning; molekylärbiologi; Molecular Biology; ortopedi; Orthopaedics;

    Abstract : In this study, the biosynthesis of proteoglycans (PGs) was examined in articular cartilage of canine hip joint after long-distance running experiment and in bovine chondrocyte cultures during in vitro loading with hydrostatic pressure. In addition, new assays were developed for more sensitive quantitation of glycosaminoglycans (GAGs) and PGs. READ MORE

  7. 5. Cartilage Tissue Engineering; the search for chondrogenic progenitor cells and associated signalling pathways

    Author : Maria Thornemo; Göteborgs universitet; []
    Keywords : stem cell; progenitor cell; tissue engineering; cartilage; articular chondrocytes;

    Abstract : The socioeconomic cost of articular cartilage related diseases in the Western world is very high. The suffering of the individual patient is even more problematic. READ MORE