Search for dissertations about: "artificial enzyme"

Showing result 1 - 5 of 49 swedish dissertations containing the words artificial enzyme.

2. 1. Theoretical modeling of metal- and enzyme catalyzed transformations

   Author : Jonas Nyhlén; Jan-Erling Bäckvall; Timofei Privalov; Walter Thiel; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; density functinal theory; computational chemistry; directed evolution; enzyme; mechanistic studies; catalysis; ruthenium; hydrogen transfer; racemization; artificial photosynthesis; frustrated lewis pairs; hydrogen storage; Organic chemistry; Organisk kemi; organisk kemi; Organic Chemistry;

   Abstract : This thesis is focused on describing and predicting catalytic reactions. The major part of the work is based on density functional theory (DFT). In some cases where the size of the investigated system precluded the use of more accurate methods molecular dynamics was employed. READ MORE

4. 2. Creating Ultrafast Biosensors for Neuroscience

   Author : Yuanmo Wang; Chalmers tekniska högskola; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; quantification; glucose; choline oxidase; gold nanoparticles; enzyme monolayer; enzymatic activity; Biosensor; adsorption; brain slice; enzyme stability; acetylcholine esterase; artificial cell; exocytosis; glucose oxidase; deformation; glutamate; glutamate oxidase; acetylcholine; amperometry;

   Abstract : Neuronal communication is the basis for all our brain function and relies on regulated exocytosis, a cell function that involves release of quantal amounts of neurotransmitters into the gap space between interconnected neurons to serve as chemical signals. To study exocytosis, which is a fast process that occurs on the timescale of sub-milliseconds to milliseconds, a toolbox of analytical methods has been developed where the electrochemical based techniques offer quantitative and sufficient high temporal recording speed. READ MORE

5. 3. Experimental and computational exploration of enzyme sequence space

   Author : Elzbieta Rembeza; Chalmers tekniska högskola; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; high-throughput-screening; protein annotation; enzyme discovery; enzyme sequence space; oxidases;

   Abstract : Millions of enzymes with desirable features or new exciting activities can be found in organisms occupying diverse niches all around the earth. However, enzyme studies tend to be biased towards characterisation of representatives from eukaryotes, model organisms, or disease-causing bacteria. READ MORE

6. 4. New Roads for an Ancient Enzyme : Whole-Cell Studies and New Cofactors for [FeFe] Hydrogenases

   Author : Marco Lorenzi; Gustav Berggren; Hannah Shafaat; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; [FeFe] hydrogenases; hydrogen; catalysis; photocatalysis; spectroscopy; whole-cell; semi-artificial enzymes; Chemistry with specialization in Molecular Biomimetics; Kemi med inriktning mot molekylär biomimetik;

   Abstract : [FeFe] hydrogenases rare Nature’s best H2-processing catalysts, and one of the best candidates to satisfy societal need for cheap and efficient catalyst for H2-evolution. These enzymes owe their remarkable catalytic activities to their organometallic active site, called “H-cluster”. READ MORE

7. 5. Electrochemical (bio-)sensors operating in human physiological fluids

   Author : Carolin Psotta; Sergey Shleev; Magnus Falk; Evgeny Katz; Malmö universitet; []
   Keywords : biosensor; bacteria; enzyme; sensor; physiological fluid;

   Abstract : This thesis is focused on developing electrochemical (bio-)sensors specifically designed to detect biomolecules and bacteria in human physiological fluids. A more comprehensive understanding of their performance can be obtained by exposing the sensors to real human physiological fluids. READ MORE