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Showing result 1 - 5 of 34 swedish dissertations matching the above criteria.
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1. Aseptic Loosening of Orthopedic Implants : Osteoclastogenesis Regulation and Potential Therapeutics
Abstract : Aseptic loosening is the main cause of failure of orthopedic prostheses. With no pharmaceuticals to prevent or mitigate periprosthetic bone degradation, a surgery to replace the loose implant with a new one is the only choice to restore patients’ function. READ MORE
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2. On the aetiology of aseptic loosening in joint arthroplasties, and routes to improved cemented fixation
Abstract : Background: Aseptic loosening is the most common single cause for revisions in major joint arthroplasties worldwide. Different theories for aseptic loosening have been discussed during the last two decades. There is a need for improving fixation in both cemented and uncemented implants. READ MORE
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3. Biological aspects of synovial fluid mediated aseptic prosthesis loosening
Abstract : Aseptic prosthesis loosening is the most common reason for late failure of total hip arthroplasties. Resorption of the peri-prosthetic bone, resulting in a loose prosthesis is characteristic for aseptic loosening. READ MORE
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4. Kinematics and fixation of total knee arthroplasties : a clinical, radiographic, scintimetric, and roentgen stereophotogrammetric evaluation
Abstract : Aseptic loosening of the tibial component is an important cause of failure after total knee arthroplasty. Bone destruction often claimed to be caused by the cement makes the revision difficult. In order to treat younger patients, uncemented fixation has been introduced, but the etiology to loosening is multifactorial and only partly known. READ MORE
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5. On loosening and revision in total hip arthroplasty
Abstract : Periprosthetic bone resorbtion (osteolysis) and aseptic loosening constitute the major long-term complication in total hip arthroplasty. It has been suggested that osteolysis is the result of the action of osteoclasts generated by prosthetic wear-debris-triggered macrophages. READ MORE