Search for dissertations about: "asm"

Showing result 1 - 5 of 16 swedish dissertations containing the word asm.

  2. 1. Extracting Genomic Variations using Selector Technology

    Author : Magnus Isaksson; Mats Nilsson; Radoje Drmanac; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Selector; Selector probe; Genetic variation; Resequencing; Targeted sequencing; copy-number variations; MLGA; Bioinformatics; Next generation sequencing; NGS; Amplified single molecule; ASM; Molecular medicine genetics and pathology ; Molekylär medicin genetik och patologi ; Genetics; Genetik; Molekylär medicin; Molecular Medicine;

    Abstract : This thesis describes the development and use of a new class of molecular tools called Selector probes, and its potential for investigations of genetic variation. The Selector technology provides multiplex amplification of targeted DNA sequences with a high specificity, and an enrichment factor in the same order of magnitude as PCR. READ MORE

  4. 2. Airway smooth muscle as a target in asthma : new insights into bronchorelaxation and hyperreactivity

    Author : Martijn Manson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Patients with asthma suffer from reversible airway obstruction accompanied by airway hyperresponsiveness (AHR). Airway smooth muscle (ASM) is central to bronchoconstriction and AHR and is therefore the target of existing and potential new therapies for asthma. READ MORE

  5. 3. Machine learning and big data for personalized epilepsy treatment

    Author : Samuel Håkansson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; anti-seizure medication; personalized treatment; machine learning;

    Abstract : Finding an effective anti-seizure medication (ASM) with minimal side effects is a challenge. Patient characteristics are used to guide treatment selection, but about half of the patients with epilepsy do not achieve seizure freedom with their first ASM. READ MORE

  6. 4. Towards Intelligent Deformable Models for Medical Image Analysis

    Author : Ghassan Hamarneh; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; shape modeling; deformable models; principal component analysis; echocardiography; snakes; active shape models; deformable spatio-temporal shape models; medial-based shape profiles; statistical shape variation; spatio-temporal shape analysis; magnetic resonance imaging; hierarchical regional principal component analysis; oral lesions; dynamic programming; segmentation; spring-mass model; shape deformation; optical flow; medical image analysis; artificial life; physics-based modeling; deformable organisms; digital color images; medial axis; active contour models;

    Abstract : Medical imaging continues to permeate the practice of medicine, but automated yet accurate segmentation and labeling of anatomical structures continues to be a major obstacle to computerized medical image analysis (MIA). Deformable models, with its profound roots in estimation theory, optimization, and physics-based dynamical systems, represent a powerful approach to the general problem of medical image segmentation. READ MORE

  7. 5. Crop and weed discrimination using computer vision

    Author : Maria Persson; Chalmers University of Technology; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Image analysis; Crops; Weeds; Other information technology; Övrig informationsteknik;

    Abstract : The thesis is concerned with computer vision in ecological and precision agriculture aiming to identify crops and weeds in images of crop rows. The identification of plants can be done by extracting the plants in the image and classifying them as a crop or weed depending on the shape and color. READ MORE