Search for dissertations about: "association mapping"

Showing result 1 - 5 of 99 swedish dissertations containing the words association mapping.

  1. 1. Genetic Mapping of Susceptibility Genes for Systemic Lupus Erythematosus

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Bo Johanneson; Uppsala universitet.; [2002]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular genetics; Association analysis; Candidate gene; Complex disease; Genome scan; Linkage analysis; Mapping; Susceptibility genes; Systemic lupus erythematosus; Genetik; NATURAL SCIENCES Biology Cell and molecular biology Genetics; NATURVETENSKAP Biologi Cell- och molekylärbiologi Genetik; medicinsk genetik; Medical Genetics;

    Abstract : Systemic lupus erythematosus (SLE) is a complex autoimmune disease with unknown etiology. The aim of this thesis was to identify susceptibility regions through genetic mapping, using model-based linkage analysis on nuclear and extended SLE multicase families. READ MORE

  2. 2. Functional association networks for disease gene prediction

    University dissertation from Stockholm : Department of Biochemistry and Biophysics, Stockholm University

    Author : Dimitri Guala; Stockholms universitet.; [2017]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; network biology; biological networks; network prediction; functional association; functional coupling; network integration; functional association networks; genome-wide association networks; gene networks; protein networks; fret; functional enrichment analysis; network cross-talk; pathway annotation; gene prioritisation; network-based gene prioritization; benchmarking; biokemi med inriktning mot bioinformatik; Biochemistry towards Bioinformatics;

    Abstract : Mapping of the human genome has been instrumental in understanding diseasescaused by changes in single genes. However, disease mechanisms involvingmultiple genes have proven to be much more elusive. Their complexityemerges from interactions of intracellular molecules and makes them immuneto the traditional reductionist approach. READ MORE

  3. 3. Dissecting the Genetic Basis of Systemic Lupus Erythematosus The Pursuit of Functional Variants

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Angélica María Delgado Vega; Uppsala universitet.; [2013]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Systemic Lupus Erythematosus; SLE; Genetic Mapping; Association Studies; Functional Variants; TNFSF4; STAT4; IRF5; CD226; BLK; BANK1; Systemisk Lupus Erythematosus; SLE; Genetik; Genetisk Association; Funktionella Varianter; TNFSF4; STAT4; IRF5; CD226; BLK; BANK1; Lupus Eritematoso Sistémico; LES; Estudios de Asociación Genética; Variantes Funcionales; TNFSF4; STAT4; IRF5; CD226; BLK; BANK1; Medical Genetics; Medicinsk genetik; Medical Science; Medicinsk vetenskap;

    Abstract : Systemic lupus erythematosus (SLE) is a chronic and systemic autoimmune disease that primarily affects women during the childbearing years. SLE is characterized by the production of autoantibodies against nucleic acids and their interacting proteins. READ MORE

  4. 4. Genomic strategies towards the dissection of human complex disease

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Tesfai Emahazion; Uppsala universitet.; [2001]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Mapping; complex disease; polymorphism; SNP; association analysis; Alzheimer s disease; oxidative phosphorylation; apoptosis; Genetik; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Clinical genetics; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Klinisk genetik; Medical Genetics; medicinsk genetik;

    Abstract : Complex diseases are caused by the activities of many genes acting in concert with environmental factors. A major challenge facing human genetic research is to unravel the genetic factors behind complex disorders. READ MORE

  5. 5. Local visual feature based localisation and mapping by mobile robots

    University dissertation from Örebro : Örebro universitet

    Author : Henrik Andreasson; Örebro universitet.; [2008]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; mobile robotics; registration; localisation; SLAM; mapping; omnidirectional vision; 3D vision; appearance based; TECHNOLOGY; TEKNIKVETENSKAP; TECHNOLOGY Information technology Computer science; TEKNIKVETENSKAP Informationsteknik Datavetenskap; Computer and Systems Science; Data- och systemvetenskap;

    Abstract : This thesis addresses the problems of registration, localisation and simultaneous localisation and mapping (SLAM), relying particularly on local visual features extracted from camera images. These fundamental problems in mobile robot navigation are tightly coupled. READ MORE