Search for dissertations about: "association mapping"
Showing result 26 - 30 of 127 swedish dissertations containing the words association mapping.
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26. Spatial Statistics and Ancestral Recombination Graphs with Applications in Gene Mapping and Geostatistics
Abstract : This thesis explores models and algorithms in geostatistics and gene mapping. The first part deals with the use of computationally effective lattice models for inference of data with a continuous spatial index. READ MORE
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27. Linkage and association analysis in multiple sclerosis
Abstract : Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system, which is characterized by relapsing or progressive demyelinating plaques in the brain and spinal cord. It is well established that complex genetic factors influence susceptibility to MS. READ MORE
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28. Novel Statistical Methods in Quantitative Genetics : Modeling Genetic Variance for Quantitative Trait Loci Mapping and Genomic Evaluation
Abstract : This thesis develops and evaluates statistical methods for different types of genetic analyses, including quantitative trait loci (QTL) analysis, genome-wide association study (GWAS), and genomic evaluation. The main contribution of the thesis is to provide novel insights in modeling genetic variance, especially via random effects models. READ MORE
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29. Mapping Genes Affecting Phenotypic Traits in Chicken
Abstract : The purpose of gene mapping is to understand the underlying genetics of simple and complex traits like plumage colour and growth. This thesis is based on a cross between the wild ancestor of the modern chicken, the red junglefowl, and a White Leghorn line selected for high egg mass. READ MORE
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30. Hypospadias : gene mapping and candidate gene studied
Abstract : Hypospadias is a common congenital malformation in boys, characterized by incomplete fusion of the urethral folds, abnormal opening of urethra and different degrees of curvature of the penis. In Sweden, the incidence of hypospadias is 1.14 per 300 male live-births according to the annual Swedish Malformation Registry. READ MORE