Search for dissertations about: "asthma in rats"
Showing result 1 - 5 of 10 swedish dissertations containing the words asthma in rats.
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1. Relationship between chemical structure and airway sensitizing potential for organic acid anhydrides : an animal model
Abstract : Oranic acid anhydrides (OAAs) are important reactive, low-molecular-weight industrial chemicals which induce allergic rhinitis and asthma in exposed subjects. Specific IgE has been demonstrated in a large proportion of OAA-exposed workers. READ MORE
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2. FROM DISEASE TO THE GENE - Identification of arthritis-regulating loci in rats
Abstract : Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation of the peripheral joints that eventually leads to cartilage destruction and bone erosion. The causes of RA remain largely unknown, but considerable evidence suggests a multifactorial aetiology involving both environmental and genetic factors. READ MORE
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3. Neurotrophins and nitric oxide in relation to airway responses in experimental asthma in vivo
Abstract : Asthma is an inflammatory disease of allergic or non-allergic genesis characterized by intermittent reversible airway obstruction and variable degrees of persistent airway hyperresponsiveness (AHR). Increase in AHR likely arises from augmented airway inflammation, such as associated with a late airway response. READ MORE
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4. Endothelin receptor changes during inflammation in the lung
Abstract : Endothelin-1 (ET-1) is an extremely potent smooth muscle spasmogen well known from the vascular system but also active within the airways. The importance of its proinflammatory and co-mitogenic properties has become increasingly evident, the endothelin system also having been shown to mimic the signal features of asthma, COPD and other pulmonary diseases. READ MORE
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5. Metabolism and Biological Monitoring of Organic Acid Anhydrides
Abstract : The aim of this thesis was to describe the metabolism and to develope methods for biological monitoring for two organic acid anhydrides (OAAs), namely hexahydrophthalic anhydride (HHPA) and methylhexa-hydrophthalic anhydride (MHHPA). The OAAs are reactive, low molecular weight chemicals used in vast quantities in the industry. READ MORE