Search for dissertations about: "asthma leukocyte"

Showing result 1 - 5 of 10 swedish dissertations containing the words asthma leukocyte.

  2. 1. Uridine, 4-thiouridine and isomaltitol in an asthma-like model : Anti-inflammatory and modulating effects

    Author : Chamilly Evaldsson; Srinivas Uppugunduri; Margareta Linden; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Uridine; asthma; 4-thiouridine; isomaltitol; isomalt; inflammation; eosinophilia; Sephadex; animal model; rat; Pharmaceutical pharmacology; Farmaceutisk farmakologi; MEDICINE; MEDICIN; Lung diseases; Lungsjukdomar;

    Abstract : In chronic inflammatory diseases like asthma or rheumatoid arthritis, erroneous and exaggerated accumulation of leukocytes in a tissue inadvertently causes the body harm. Several efficient anti-inflammatory drugs exist, for example corticosteroids and cyclo-oxygenase inhibitors. READ MORE

  4. 2. Epigenetic mechanisms of asthma and allergy

    Author : Nathalie Acevedo; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Allergic diseases such as atopic eczema (AE) and asthma are chronic inflammatory disorders in which the regulation of the immune system is altered, in concert with disease-specific defects in target organs. Their inception requires gene-environment interactions but the molecular mechanisms contributing to the pathogenesis remain unclear. READ MORE

  5. 3. Neurotrophins and nitric oxide in relation to airway responses in experimental asthma in vivo

    Author : Lydia Bennedich Kahn; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Asthma is an inflammatory disease of allergic or non-allergic genesis characterized by intermittent reversible airway obstruction and variable degrees of persistent airway hyperresponsiveness (AHR). Increase in AHR likely arises from augmented airway inflammation, such as associated with a late airway response. READ MORE

  6. 4. Endogenous and exogenous glucocorticoid effects in a model of allergic airway inflammation

    Author : Susanna Kumlien Georén; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Airway; allergy; asthma; eosinophil; glucocorticoids; hypothalamus-pituitary-adrenal HPA axis; inflammation; nerve growth factor NGF ; neuroimmunology; psychoneuroimmunology; restraint; stress;

    Abstract : Allergic asthma and rhinitis are inflammatory diseases of the airways. Allergic asthma is characterized by eosinophilic inflammation, reversible bronchoconstriction and airway hyperresponsiveness, whereas patients with rhinitis suffer from nasal inflammation, leading to rhinorrhea and nasal congestion. READ MORE

  7. 5. Effects of Inflammatory Mediators on Pulmonary Airways

    Author : Ofir Bachar; Klinisk och experimentell allergiforskning; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; electric ?eld stimulation; bradykinin; airway; tumor necrosis factor a; Respiratory system; nitric oxide; Andningsorganen; Toll-like receptor; prostaglandin E2; neurotrophin; allergy;

    Abstract : Chronic inflammation is together with excessive contraction of the airways key features of asthma. The aims of the thesis were to analyze the effect of inflammatory mediators on airway smooth muscle, using an in vitro model of cultured murine airways. READ MORE