Search for dissertations about: "asymmetric cell division"
Showing result 1 - 5 of 11 swedish dissertations containing the words asymmetric cell division.
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1. Genetic mechanisms regulating proliferation and cell specification in the Drosophila embryonic CNS
Abstract : The central nervous system (CNS) consists of an enormous number of cells, and large cellular variance, integrated into an elaborate network. The CNS is the most complex animal organ, and therefore its establishment must be controlled by many different genetic programs. READ MORE
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2. On protein oxidation, lifespan and aging in Saccharomyces cerevisiae
Abstract : In this thesis, we have investigated the physiology of protein oxidation and its possible role in the aging of the yeast Saccharomyces cerevisiae. There are two ways to measure yeast aging. First, they can only divide a finite number of times even when all nutrients necessary for division are provided. This is replicative aging. READ MORE
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3. On chaperone co-operation in temporal and spatial protein quality control
Abstract : In order for a protein to be able to function correctly it needs to adopt its proper fold. Because of this, protein quality control (PQC) is vital at every level of cellular function. The central protein in PQC networks across all kingdoms of life are the Hsp70 molecular chaperones. READ MORE
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4. Roles of Notch signalling in early embryonic development
Abstract : Metazoan embryonic development requires a complex interplay of morphological processes coordinated with self-renewal and differentiation to correctly specify and maintain body cell types in the correct location. Notch signalling is a metazoan specific arbiter of cell fate decision processes, known to control lateral inhibition and asymmetric cell division processes throughout the metazoa and in the development of all metazoan organs. READ MORE
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5. Damage Segregation and Cellular Rejuvenation in Saccharomyces cerevisiae
Abstract : The process of aging is defined as a time-dependent decline in cellular functionality, and aging is thought to have evolved as organisms were optimized for reproduction, at the cost of an imperfect repair and maintenance system. As a consequence, different kinds of dysfunctional components and damage accumulate over time. READ MORE