Search for dissertations about: "atherosclerosis"

Showing result 1 - 5 of 466 swedish dissertations containing the word atherosclerosis.

  2. 1. Inflammation in atherosclerosis

    Author : Ken Jatta; Allan Sirsjö; Michael D. Menger; Örebro universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Atherosclerosis; chemokine; cytokine; inflammation; Lipopolysacchride; Carotid lesion; interleukin; viperin Cig5; smooth muscle cells; Cardiovascular medicine; Kardiovaskulär medicin; MEDICINE; MEDICIN; Biomedicin; Biomedicine;

    Abstract : Consequences of atherosclerosis may result in a number of diseases of the cardiovascular system that represent serious health problems and major causes of morbidity and mortality worldwide. Although it is initially considered as disease of fibro-lipid and thrombus deposition in the arterial wall, it also involves an ongoing inflammatory response. READ MORE

  4. 2. CXCL16 and CD137 in atherosclerosis

    Author : Dick Wågsäter; Allan Sirsjö; Ewa Ehrenborg; Örebro universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; atherosclerosis; chemokine; cytokine; endothelial cells; inflammation; low-density lipoprotein; macrophages; scavenger receptor; smooth muscle cells; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; MEDICINE; MEDICIN; Biomedicin; Biomedicine;

    Abstract : Atherosclerosis is a progressive inflammatory disease that is characterized by the accumulation of lipids, infiltrated cells and fibrous elements in large arteries. This thesis focuses on the molecular mechanisms behind foam cell formation and inflammation, two central processes in the development of atherosclerosis. READ MORE

  5. 3. IL-25 and B cells in atherosclerosis

    Author : Polyxeni Mantani; Kardiovaskulär forskning - immunitet och ateroskleros; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IL-25; B cells; ILC2s; IL-5; anti-PC IgM; atherosclerosis; stroke; cardiovascular events;

    Abstract : Atherosclerosis is a chronic inflammatory disease of medium and large vessels of the body which is mainly characterized by the formation of lipid rich plaques within the arterial tissue. It is the most common cause of cardiovascular disease leading to clinical manifestations of coronary artery and cerebrovascular disease. READ MORE

  6. 4. Modulaton of gene expression in human aortic smooth muscle cells by Porphyromonas gingivalis : a possible association between periodontitis and atherosclerosis

    Author : Boxi Zhang; Torbjörn Bengtsson; Allan Sirsjö; Hazem Khalaf; Julia Davies; Örebro universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microarray; Angiopoietin; Smooth muscle cells; TNF; Periodontitis; Atherosclerosis; Porphyromonas gingivalis; Cancer; Inflammasome; Biomedicin; Biomedicine;

    Abstract : Porphyromonas gingivalis is a gram-negative, rod-shaped, and anaerobic bacterium that is involved in the pathogenesis of periodontitis. P. gingivalis produces a variety of virulence factors including gingipains and fimbriae. READ MORE

  7. 5. Macrophage Activation and AP-1 in Atherosclerosis

    Author : Maria Stollenwerk; Kardiovaskulär forskning - immunitet och ateroskleros; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kardiovaskulära systemet; Proteins; enzymology; Proteiner; enzymologi; Cardiovascular system; carotid plaque; interleukin-1b; caspase-1.; very low-density lipoprotein; fatty acids; activator protein-1; inflammation; Atherosclerosis; nuclear factor-kB; macrophages; tumor necrosis factor;

    Abstract : High levels of very low density lipoprotein (VLDL) and intermediate density lipoprotein (IDL) have been identified as independent risk factors for coronary heart disease. Hypertriglyceridemia is generally associated with an increased expression of inflammatory makers and inflammation is thought to contribute to atherosclerosis and its complications. READ MORE