Search for dissertations about: "autoimmune arthritis"
Showing result 1 - 5 of 210 swedish dissertations containing the words autoimmune arthritis.
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1. B cells in Autoimmunity : Studies of Complement Receptor 1 & 2 and FcγRIIb in Autoimmune Arthritis
Abstract : B cells are normally regulated to prevent activation against self-proteins through tolerance mechanisms. However, occasionally there is a break in tolerance and B cells can become self-reactive, which might lead to the development of autoimmune disease. READ MORE
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2. Genetic Studies of Rheumatoid Arthritis using Animal Models
Abstract : Predisposition to autoimmune diseases such as, rheumatoid arthritis, diabetes, and multiple sclerosis, is caused by the effect of multiple genes and a strong influence from the environment. In this study, I have investigated genetic factors that confer susceptibility to rheumatoid arthritis in a rat model. READ MORE
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3. T lymphocytes in autoimmune arthritis : monoclonal antibody treatments in mouse and rat
Abstract : .... READ MORE
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4. Function and Regulation of B-cell Subsets in Experimental Autoimmune Arthritis
Abstract : B lymphocytes play a significant role in autoimmune arthritis, with their function stretching beyond autoantibody production to cytokine secretion and presentation of autoantigen. However, the involvement and activation of different B-cell subset in the autoimmune response is not fully clear. READ MORE
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5. Analysis of effector pathways in arthritis
Abstract : Rheumatoid arthritis (RA) is a multifactorial, polygenic autoimmune disease. For effective treatment and control of RA, understanding of disease pathways and identification of genes involved are essential. Animal models are efficient tools to identify such pathogenic mechanisms and genes underlying the disease process. READ MORE