Search for dissertations about: "autoimmune-disease"

Showing result 1 - 5 of 251 swedish dissertations containing the word autoimmune-disease.

  2. 1. Genetic Characterization of Chicken Models for Autoimmune Disease

    Author : Anna-Stina Sahlqvist; Olov Ekwall; Olle Kämpe; Leif Andersson; Susanne Kerje; Holger Luthman; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Autoimmune disease; Hashimoto’s thyroiditis; systemic sclerosis; comparative genomics; linkage analysis; OS chickens; spontaneous autoimmune thyroiditis; UCD-200 chickens.; Molekylär medicin; Molecular Medicine;

    Abstract : Autoimmune diseases are endemic, but the disease mechanisms are poorly understood. A way to better understand these are to find disease-regulating genes. However, this is difficult as the diseases are complex, with several genes as well as environmental factors influencing the development of disease. READ MORE

  4. 2. B cell regulation in autoimmune disease

    Author : Shan Wang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Our immune system protects us from both foreign antigens and self-derived autoantigens by sophisticated regulation. During an immune response, the innate and adaptive parts of the immune system closely collaborate at every stage of the response. READ MORE

  5. 3. Multifunctional roles of plasmin in inflammation : Studies of animal models on rheumatoid arthritis, multiple sclerosis, wound healing and infection

    Author : Jinan Li; Peter Carmeliet; Umeå universitet; []
    Keywords : Plasmin; complement; inflammation; wound healing; infection; autoimmune disease; non-autoimmune disease; rheumatoid arthritis; multiple sclerosis; tympanic membrane; otitis media; medicinsk biokemi; Medical Biochemistry;

    Abstract : Plasmin has been suggested to be involved in degradation of extracellular matrix (ECM) and tissue remodeling during a number of physiological and pathological processes. The aims of this thesis were to study the functional roles of plasmin during pathological inflammation in autoimmune and nonautoimmune disease models of rheumatoid arthritis (RA), multiple sclerosis (MS), wound healing and infection. READ MORE

  6. 4. Genetic studies of complex autoimmune disease

    Author : Alexandra Gyllenberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : In complex autoimmune diseases, there are both genetic and environmental factors that influence our immune system and contribute to the development of disease. The pathways, interactions and mode of inheritance are difficult to unravel, and many discoveries are yet to be done. READ MORE

  7. 5. B cell subsets in autoimmune disease

    Author : Katrin Habir; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : B lymphocytes are a type of white blood cells, belonging to the adaptive arm of the immune system and involved in creating immunological memory. B cells function in the humoral immune system by secreting antibodies which can bind pathogens to prevent them from doing further damage and to help other immune cells to target them. READ MORE