Search for dissertations about: "autophagy"

Showing result 11 - 15 of 115 swedish dissertations containing the word autophagy.

  2. 11. Modulation of PDGF receptors function by posttranslational modifications

    Author : Kehuan Wang; Carl-Henrik Heldin; Johan Lennartsson; Natalia Papadopoulos; Jean-Baptiste Demoulin; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PDGF signaling; receptor tyrosine kinase; ubiquitination; DUB; STAT3; SUMO; SUMOylation; cleavage; autophagy; SQSTM1 p62; LC3; GABARAP; bafilomycin A1; Medicinsk biokemi; Medical Biochemistry; Medical Cell Biology; Medicinsk cellbiologi;

    Abstract : The platelet-derived growth factor receptors (PDGFRs) play important roles in multiple cellular processes including cell survival, cell growth and cell migration. Dysregulation of PDGFRs causes aberrant PDGF signaling, which leads to various diseases. READ MORE

  4. 12. Programmed Cell Death in Xylem Development

    Author : Laetitia Charleen Courtois-Moreau; Hannele Tuominen; Stefan Jansson; Christina Dixelius; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; PCD Programmed Cell Death ; Xylem; Apoptosis; Autophagy; Secondary Cell Walls; Microscopy; Microarrays; Comet Assay; TUNEL Assay; Cell and molecular biology; Cell- och molekylärbiologi;

    Abstract : Concerns about climate changes and scarcity of fossil fuels are rising. Hence wood is becoming an attractive source of renewable energy and raw material and these new dimensions have prompted increasing interest in wood formation in trees, in both the scientific community and wider public. READ MORE

  5. 13. Laboratory Soft X-Ray Cryo Microscopy: Source, System and Bio Applications

    Author : Emelie Fogelqvist; Hans Hertz; David Attwood; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; X-ray microscopy; X-ray optics; Instrumentation; Laser plasma; Cryofixation; Tomography; Tomographic reconstruction; Autophagy; Immune synapse; Physics; Fysik; Physics;

    Abstract : Soft x-ray microscopes routinely perform high-resolution 3D imaging of biological cells in their near-native environment with short exposure times at synchrotron radiation facilities. Some laboratory-sized microscopes are aiming to make this imaging technique more accessible to a wider scientific community. READ MORE

  6. 14. Molecular And Cellular Networks in Critical Illness Associated Muscle Weakness : Skeletal Muscle Proteostasis in the Intensive Care Unit

    Author : Varuna Chaminda Banduseela; Lars Larsson; Gustavo Nader; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chaperones; autophagy; intensive care unit; heat shock proteins; protein synthesis; proteostasis; ER stress; gene expression; sepsis; neuromuscular blockers; corticosteroids; immobilisation; mechanical ventilation; Molekylär cellbiologi; Molecular Cellbiology; Molekylär medicin; Molecular Medicine;

    Abstract : Critical illness associated muscle weakness and muscle dysfunction in intensive care unit (ICU) patients lead to severe morbidity and mortality as well as significant adverse effect on quality of life. Immobilization, mechanical ventilation, neuromuscular blocking agents, corticosteroids, and sepsis have been implicated as important risk factors, but the underlying molecular and cellular mechanisms remain unclear. READ MORE

  7. 15. Roles of membrane vesicles in bacterial pathogenesis

    Author : Svitlana Vdovikova; Sun Nyunt Wai; Richard Lundmark; Ann-Beth Jonsson; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Membrane vesicles; autophagy; pore-forming toxin; pore formation; Listeria monocytogenes; Vibrio cholerae; virulence factor; PrtV protease; listeriolysin O; V. cholerae cytolysin; mikrobiologi; Microbiology; molekylärbiologi; Molecular Biology;

    Abstract : The production of membranous vesicles is observed to occur among organisms from all domains of the tree of life spanning prokaryotes (bacteria, archaea) and eukaryotes (plants, animals and fungi). Bacterial release of membrane-derived vesicles (MVs) has been studied most extensively in cases of Gram-negative species and implicating their outer membrane in formation of extracellular MVs. READ MORE