Search for dissertations about: "autophagy"

Showing result 21 - 25 of 115 swedish dissertations containing the word autophagy.

  2. 21. Deposition and Resolution of AA Amyloid

    Author : Sofia N. Nyström; Gunilla T Westermark; Christoph Röcken; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; AA-amyloid; autophagy; resolution; Morphology; cell biology; pathology; Morfologi; cellbiologi; patologi;

    Abstract : Amyloidosis is a group of protein misfolding diseases characterized by extracellulardeposition of fibrillar protein aggregates. Today more than 25 different human amyloidogenicproteins have been identified, causing a variety of pathological conditions that includeAlzheimer’s disease, type 2 diabetes and prion diseases. READ MORE

  4. 22. Caspase-dependent and caspase-independent neuronal injury in the developing brain

    Author : Changlian Zhu; Göteborgs universitet; []
    Keywords : hypoxia ischemia; neonatal; cell death; caspase; apoptosis-inducing factor; brain; apoptosis; autophagy; nitric oxide;

    Abstract : Aims: To investigate the mechanisms of neuronal cell death after hypoxia-ischemia in the developing brain.Methods: Rats or mice were subjected to left common carotid artery ligation plus hypoxia. Animals were sacrificed at certain time points after hypoxia-ischemia. READ MORE

  5. 23. Characterisation of autophagy pathways in atherosclerosis

    Author : Peter Saliba Gustafsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Atherosclerosis is an inflammatory disease of large to intermediate-sized arteries, characterised by retention of modified low-density lipoprotein within the vessel wall; this evokes an inflammatory response. Low-density lipoprotein carries lipids such as fatty acids, triglycerides and cholesterol, from the liver to peripheral tissues. READ MORE

  6. 24. Lipid Metabolism and Insulin Signalling in Adipocytes : enhanced autophagy in type 2 diabetes

    Author : Anita Öst; Peter Strålfors; Johanna Gustavsson Dahlberg; Anna Krook; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Energy storage in the adipose tissue, to an extent leading to obesity, is associated with local as well assystemic insulin resistance. When insulin-producing beta-cells in the pancreas gradually fail tocompensate, plasma levels of glucose rise and overt type 2 diabetes is diagnosed. READ MORE

  7. 25. Short and long-term regulation of autophagy

    Author : Patricia González-Rodríguez; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Autophagy is a conserved catabolic pathway triggered by stress conditions in which portions of the cytoplasm, damage organelles, misfolded proteins and intracellular bacteria are delivered and degraded in the lysosome/vacuoles. Thus, an efficient induction and completion of the process is required to ensure a proper homeostasis of the cell. READ MORE