Search for dissertations about: "autoradiography"
Showing result 21 - 25 of 95 swedish dissertations containing the word autoradiography.
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21. Distribution of serotonin receptors and transporters in the human brain : implications for psychosis
Abstract : The serotonin (5-HT) system is thought to be involved in different psychiatric disorders, including depression and anxiety disorders, and is a major target for the pharmacological treatment of these conditions. The involvement of the 5-HT system in psychosis has been suggested, as 5-HT receptor agonism is a common mechanism of different classes of hallucinogenic drugs and several antipsychotics are 5-HT receptor antagonists. READ MORE
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22. Methological advances in the examination of the dopamine system in brain
Abstract : The dopamine (DA) system in brain has attracted considerable attention in neuroscience due to its involvement in fundamental brain functions and its postulated role in the pathophysiology of several neuropsychiatric disorders. Radioligand binding techniques in vitro and in vivo, such as receptor binding autoradiography and positron emission tomography (PET) have substantially contributed to our understanding of the DA system. READ MORE
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23. Distribution and regulation of neuropeptide Y and its receptors in the human and rat brain : role in affective disorders
Abstract : Neuropeptide Y (NPY) is one of the most abundant peptides found within the mammalian brain. Many studies have documented that this 36-amino acid peptide exerts a wide range of central effects. READ MORE
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24. Physiology and pathophysiology of central adenosine A1 and A2A receptors
Abstract : The aim of this thesis was to further investigate the individual roles of central adenosine A1 and A2A receptors in the physiological and pathophysiological effects of adenosine. In addition, the characteristics of different adenosine receptor ligands were studied. READ MORE
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25. Somatostatin neurotransmission : studies on experimentally induced cognitive changes and Alzheimer’s disease
Abstract : Several neuropeptides are widely distributed in regions of the central nervous system (CNS) which are associated with cognitive functions. Multiple studies on postmortem Alzheimer's disease (AD) brains have shown depleted neuropeptide content and morphological abnormalities of somatostatin (SS)-containing interneurons in the hippocampus and the cerebral cortex. READ MORE