Search for dissertations about: "auxiliary protein"
Showing result 16 - 20 of 26 swedish dissertations containing the words auxiliary protein.
-
16. Intracellular pathways involved in formation and degradation of prions
Abstract : Prions cause invariably fatal neurodegenerative diseases, in which a misfolded host-encoded protein appears to be the main, if not the only, component of the infectious agent. During disease, a normal cellular protein, PrPC, is converted to a disease-related isoform, PrPSc, by a post-translational process that might require auxiliary cellular cofactors. READ MORE
-
17. Characterization of ERp29 : a novel secretion factor of endoplasmic reticulum
Abstract : ERp29 is a ubiquitously expressed endoplasmic reticulum protein strongly conserved in mammalian species. The N-terminal domain of ERp29 is similar to the thioredoxin domain of protein disulfide isomerase (PDI) lacking however the double-cysteine active site motif. The C-terminal domain is a novel five-helical fold. READ MORE
-
18. Comparative genomics and molecular characterization of N-alpha acetyltransferase in trypanosomes for drug target identification
Abstract : Trypanosoma cruzi and Trypanosoma brucei are flagellated protozoan parasites that cause Chagas disease and African trypanosomiasis in Latin American and African countries, respectively. Currently, over 8 million people are infected with T. cruzi and about 25 million more are at risk. About half a million people are affected by T. READ MORE
-
19. Characterization of GTPBPs involved in ribosome assembly and function in human mitochondria
Abstract : Mitochondria are organelles often referred to as the powerhouses of the cell as they provide most of the chemical energy via aerobic respiration. However, in the last half a century, it has become clear that their function extends to other fundamental metabolic tasks. READ MORE
-
20. The role of HIF-1alpha in epigenetic regulation of transcription
Abstract : The oxygen level inside cells, determine the amount of HIF protein. By directly being involved in HIF protein turnover rates, through a mechanism, by which, oxygen is utilized as a co-factor, for the PHD enzymes, regulating HIF protein stability. READ MORE