Search for dissertations about: "axotomy"
Showing result 1 - 5 of 40 swedish dissertations containing the word axotomy.
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1. Transcriptional regulation of the neuropeptide galanin : special reference to axotomy
Abstract : Galanin is a neuropeptide which is located in both the central and peripheral nervous system. In peripheral neurones, this peptide is thought to be involved in influencing pain sensation after nerve injury (neuropathic pain) and also in the regeneration of peripheral nerves. READ MORE
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2. Autoimmune and innate inflammation in the nervous system : neurotrophin production and impact on neuronal survival
Abstract : The occurrence of a continuous immune surveillance in the central nervous system (CNS) is a fairly recent finding. For long the CNS was considered an immune privileged organ, with the blood-brain barrier constituting an effective barrier against blood-derived molecules and cells. READ MORE
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3. Genetics and inflammation in nerve injury-induced neurodegeneration
Abstract : Neurodegeneration and inflammation are characteristic of many diseases of the central nervous system (CNS) and understanding the molecular networks that regulate these processes is of central importance for the development of effective therapies. Although the CNS has traditionally been regarded as an immuno privileged organ, immune reactions, including components of both local innate and systemic immunity, do occur in this tissue. READ MORE
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4. Neuropeptide release in the rat dorsal horn in models of persistent pain : effects of opioids
Abstract : Nerve injury and tissue inflammation may lead to exaggerated responses to both noxious stimuli (hyperalgesia) and innocuous stimuli (allodynia). Altered release pattems of neurotransmitters in the dorsal hom of the spinal cord have been suggested to contribute to hyperalgesia and allodynia. READ MORE
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5. Spinal motoneurons and molecules related to neurotrophic function after axon injury
Abstract : The capacity of motoneurons to survive and regenerate new axons after injuries such as axotomy depends on a great variety of parameters. After sciatic nerve transection (SNT) in adult rats and to some extent after a ventral funiculus lesion (VFL), many cells survive and regeneration is highly prioritized. READ MORE