Search for dissertations about: "b10 cell"

Showing result 1 - 5 of 9 swedish dissertations containing the words b10 cell.

  2. 1. Dendritic cell presentation of type II collagen

    Author : Meirav Holmdahl; Lund Dermatologi och venereologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin människa och djur ; Medicine human and vertebrates ; chromosome 2; arthritis; proteases; antigen presentation; Dendritic cell; type II collagen;

    Abstract : Type II collagen (CII) is the main protein component of cartilage and immune recognition of CII plays a critical role for the development of collagen induced arthritis (CIA), a widely used animal model for rheumatoid arthritis (RA). Antigen presentation is an important requirement for the immune response, the more efficient presentation of the antigen the better tolerance will be induced and thereby protect against arthritis. READ MORE

  4. 2. Investigation of T cell driven arthritis induced by mannan in ZAP70 mutated SKG mice

    Author : Simon Guérard; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Autoimmune diseases are particularly challenging to study in human due to their complex multifactorial nature. In rheumatoid arthritis (RA), self-reactivity directed against joints leads to pain, tissue destruction and eventually invalidity if left untreated. READ MORE

  5. 3. A Search for Neutrinos from Cosmic Point Sources using AMANDA-B10 with Emphasis on Limit Calculation Techniques

    Author : Jan Conrad; Allan Hallgren; Olga Botner; Gregory W. Sullivan; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Elementary particle physics; Elementarpartikelfysik; Elementary particle physics; Elementarpartikelfysik;

    Abstract : A search for cosmic point sources of neutrinos has been performed using data taken in 1999 with the AMANDA-B10 neutrino telescope. This work describes methods for signal and background separation and the statistical analysis of the final data sample. READ MORE

  6. 4. MHC and Transgenic Mice. A study into polymorphism and function of class I and class II molecules

    Author : Mikael Vestberg; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MHC rat mouse transgenic autoimmunity collagen peptide; Clinical biology; Klinisk biologi;

    Abstract : Transplantation antigens encoded in the major histocompatibility complex (MHC) bind peptides and present them to T cells. We showed that mouse T cells expressing transgenic human CD8 can recognise human MHC class I. READ MORE

  7. 5. Identification of candidate genes involved in Mercury Toxicokinetics and Mercury Induced Autoimmunity

    Author : Hammoudi Alkaissi; Per Hultman; Said Havarinasab; Peter Söderkvist; Jesper Bo Nielsen; Johan Rönnelid; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : BACKGROUND: Autoimmune diseases require the involvement and activation of immune cells and occur when the body builds up an immune response against its own tissues. This process takes place due to the inability to distinguish self-antigen from foreign antigen. Systemic autoimmunity represents an important cause of morbidity and mortality in humans. READ MORE