Search for dissertations about: "baclofen"

Showing result 1 - 5 of 9 swedish dissertations containing the word baclofen.

  1. 1. The prefrontal cortex and information processing : nitric oxide signaling studied in an animal model of schizophrenia

    Author : Kim Fejgin; Göteborgs universitet.; Gothenburg University.; [2008]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; schizophrenia; nitric oxide; prepulse inhibition; phencyclidine; prefrontal cortex; cGMP; baclofen; cognition;

    Abstract : The prefrontal cortex has been extensively linked to several cognitive domains that are severely compromised in schizophrenia. It has therefore become a key region for studies on the disabling cognitive dysfunction commonly observed in patients with schizophrenia. READ MORE

  2. 2. Neuron-glial Interaction in the Developing Peripheral Nervous System

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Mikael Corell; Uppsala universitet.; [2011]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Schwann cell; nonmyelinating Schwann cell; myelinating Schwann cell; development; proliferation; differentiation; myelin; neural stem cell; central nervous system; peripheral nervous system; enteric nervous system; N-cadherin; GABA; GAD; GABA B receptor; baclofen; CGP55485; MEDICINE Morphology; cell biology; pathology Cell biology Neuroscience; MEDICIN Morfologi; cellbiologi; patologi Cellbiologi Neurovetenskap; Neuroscience; Neurovetenskap;

    Abstract : The nervous system, including the brain, is the most sophisticated organ in the mammalian body. In such a complex network, neuron-glial interaction is essential and controls most developmental processes, such as stem cell fate determination, migration, differentiation, synapse formation, ensheathment and myelination. READ MORE

  3. 3. Drug-enhanced spinal cord stimulation for neuropathic pain : Studies on neurochemical mechanisms and clinical applications

    University dissertation from Stockholm : Karolinska Institutet, Department of Clinical Neuroscience

    Author : Gastón Schechtmann; Karolinska Institutet.; Karolinska Institutet.; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Acetylcholine; baclofen; cholinergic analgesia; clonidine; gabapentin; neuropathic pain; nerve injury; pregabalin; spinal cord stimulation; intrathecal drug;

    Abstract : Spinal cord stimulation (SCS) is an effective surgical treatment for neuropathic pain refractory to pharmacological therapy. For many patients suffering from this type of chronic pain, SCS is in fact the ultimate treatment option. READ MORE

  4. 4. Treatment of pain behavior after spinal cord injury in rats with special emphasis on the role of adenosine receptors

    University dissertation from Stockholm : Karolinska Institutet, Department of Laboratory Sciences and Technology

    Author : Margareta von Heijne; Karolinska Institutet.; Karolinska Institutet.; [2000]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adenosine; adenosine receptors; allodynia; baclofen; central pain; clonidine; intrathecal; morphine; neuropathic pain; opioid; rat; R-phenylisopropyladenosine; spinal cord injury; tolerance;

    Abstract : Central pain is a form of neuropathic pain occurring after injury or dysfunction in the central nervous system, including the spinal cord. Allodynia (pain to innocuous stimuli) to mechanical and cold stimulation is a common feature of central pain and it is often resistant to treatment. READ MORE

  5. 5. Advances in spinal cord stimulation - enhancement of efficacy, improved surgical technique and a new indication

    University dissertation from Stockholm : Karolinska Institutet, Dept of Clinical Neuroscience

    Author : Göran Lind; Karolinska Institutet.; Karolinska Institutet.; [2012]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; spinal cord stimulation;

    Abstract : Introduction and aim: Spinal cord stimulation (SCS) has been used for treatment of otherwise therapy-resistant chronic neuropathic pain for about four decades. However, 30-40 % of the patients do not benefit from SCS, despite careful case selection and technical advances. READ MORE