Search for dissertations about: "baclofen"

Showing result 6 - 10 of 11 swedish dissertations containing the word baclofen.

  2. 6. Advances in spinal cord stimulation : enhancement of efficacy, improved surgical technique and a new indication

    Author : Göran Lind; Karolinska Institutet; Karolinska Institutet; []
    Keywords : spinal cord stimulation;

    Abstract : Introduction and aim: Spinal cord stimulation (SCS) has been used for treatment of otherwise therapy-resistant chronic neuropathic pain for about four decades. However, 30-40 % of the patients do not benefit from SCS, despite careful case selection and technical advances. READ MORE

  4. 7. Genetic and environmental influences on multiple sclerosis complications and aetiology

    Author : Kelsi Alexandra Smith; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Multiple sclerosis (MS) is an immune mediated, neurological disease that results in a chronic accumulation of disability over time. Many advances in the understanding, diagnosis and treatment of MS have been made, yet questions surrounding causes and consequences still remain. READ MORE

  5. 8. The vestibular system, a tool to study neurotoxicants in the central nervous system

    Author : Magnus Niklasson; Måns Magnusson; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : The vestibular and opto-ocular motor (VOOM) system in pigmented rats was investigated. Horizontal eye movements were recorded by the magnetic search coil technique during different kind of stimulations. The dynamics of the vestibular ocular reflex (VOR) and the optokinetic reflex (OKR) as well as the interaction of the two rel1exes were analysed. READ MORE

  6. 9. Bispyridylamides as ligands in asymmetric catalysis

    Author : Oscar Belda de Lama; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; asymmetric catalysis; chiral ligand; pyridine; amide; allylic alkylation; enantioselective; cyanation; ring-opening; chiral Lewis acid;

    Abstract : This thesis deals with the preparation and use of chiralbispyridylamides as ligands in metal-catalyzed asymmetricreactions. The compounds were prepared by amide formation usingdifferent coupling reagents. READ MORE

  7. 10. Central nervous system targets for micturition control

    Author : Rikard Pehrson; Avdelningen för klinisk kemi och farmakologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; central nervous system; Micturition; 5-HT; GABA; tramadol; NAD-299; CGP62349; apomorphine; cerebral infarction; toxikologi; farmaci; farmakognosi; Farmakologi; toxicology; pharmacy; pharmacognosy; Pharmacological sciences;

    Abstract : Normal urine storage and bladder emptying are controlled by the central (CNS) as well as the peripheral nervous system. Dysfunction of these mechanisms can lead to urinary incontinence. Urinary tract dysfunctions have symptomatically been treated mainly with drugs acting peripherally. READ MORE