Search for dissertations about: "bacterial translocation"
Showing result 6 - 10 of 74 swedish dissertations containing the words bacterial translocation.
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6. Insertion studies of model transmembrane segments into bacterial and eukaryotic membranes
Abstract : Cells are encapsulated by a biological membrane in order to separate the cell interior from the surrounding environment. Different lipids and proteins compose the membrane and present a semi-permeable barrier for the diffusion of ions and molecules across the lipid bilayer. READ MORE
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7. Delivery of TypeIII Secreted Toxins by Yersinia pseudotuberculosis : the Role of LcrV, YopD, and Free Lipids in the Translocation Process
Abstract : Bacteria that infect humans and animals face a hard combat with the host´s immune system and in order to establish infection, pathogenic bacteria has evolved mechanisms to avoid being cleared from the host tissue. Many Gram-negatives carry a Type 3 secretion (T3S) system that is used to deliver effector proteins (toxins) into host cells. READ MORE
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8. The intestinal epithelium of salmonids : transepithelial transport, barrier function and bacterial interactions
Abstract : The salmonid intestinal epithelium is important for growth and health of the fish. The epithelium is exposed to a multitude of internal and external factors that can influence its function. READ MORE
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9. Role of YopE and LcrH in effector translocation, HeLa cell cytotoxicity and virulence
Abstract : In order to establish an extra-cellular infection the gram-negative bacteria Yersinia pseudotuberculosis uses a type III secretion system (T3SS) to translocate a set of anti-host effectors into eukaryotic cells. The toxins disrupt signalling pathways important for phagocytosis, cytokine production and cell survival. READ MORE
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10. Timing and targeting of Type III secretion translocation of virulence effectors in Yersinia
Abstract : The Type III secretion system (T3SS) is an important virulence mechanism that allows pathogenic bacteria to translocate virulence effectors directly into the cytoplasm of eukaryotic host cells to manipulate the host cells in favor of the pathogen. Enteropathogenic Yersinia pseudotuberculosis use a T3SS to translocate effectors, Yops, that prevent phagocytosis by immune cells, and is largely dependent on it to establish and sustain an infection in the lymphoid tissues of a mammalian host. READ MORE