Search for dissertations about: "bactericidal"

Showing result 16 - 20 of 92 swedish dissertations containing the word bactericidal.

  2. 16. Regulation of internalization and replication of intracellular bacterial pathogens

    Author : Eugénie Bassères; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The capacity of intracellular bacteria to cause disease depends on their ability to invade and replicate within eukaryotic host cells. These characteristics also allow preferential invasion and replication by facultative anaerobic bacteria in solid tumours, which can be exploited to design delivery vectors for cancer therapy. READ MORE

  4. 17. Pathogenic Neisseria : Single cell motility, multicellular dynamics and antimicrobial susceptibility

    Author : Olaspers Sara Eriksson; Ann-Beth Jonsson; Matthew Francis; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Neisseria; Type IV pili; Twitching motility; PilT; Microcolony dynamics; PilU; NafA; Antimicrobial peptide; Cell-penetrating peptide; molekylär biovetenskap; Molecular Bioscience;

    Abstract : Neisseria meningitidis and Neisseria gonorrhoeae can colonize humans without causing any symptoms. However, gonorrhea and invasive meningococcal disease are serious health concerns. An essential virulence factor for neisserial adhesion to host cells, twitching motility and microcolony formation/aggregation is the retractile type IV pili (Tfp). READ MORE

  5. 18. Immunochemical characterisation of Brucella LPS and its relation to virulence

    Author : Enrique Freer; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Brucella abortus Brucella ovis Bacterial lipopolysaccharide LPS : LPS heterogeneity Virulence factors Cationic peptides.;

    Abstract : Members of the genus Brucella are facultative intracellular pathogens which infect and produce disease in a wide variety of mammals. Although some factors have been implicated in the virulence of Brucella, the virulence mechanisms of this intracellular pathogen are not known. READ MORE

  6. 19. Antibacterial Effect and Inflammatory Response in Relation to Antibiotic Treatment of Sepsis

    Author : Paul Skorup; Jan Sjölin; Miklós Lipcsey; Kristoffer Strålin; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Sepsis; Septic shock; Antibiotics; Aminoglycoside; β-lactam; Bacteria; E. coli; Inflammation; Cytokines; Endotoxin; Porcine; ICU; Secondary sepsis; Endotoxin-tolerance.; Infektionssjukdomar; Infectious Diseases;

    Abstract : Sepsis defines as life-threatening organ dysfunction caused by a dysregulated host response to infection. The importance of early administration of antibiotics in septic shock is undisputed, but the optimal antibiotic choice remains uncertain. READ MORE

  7. 20. Human mononuclear phagocytes : Production of reactive oxygen species generated by the NADPH oxidase

    Author : Agneta Johansson; Roger Sundler; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Human professional phagocytes constitute the first line of defence against invading microorganisms. With a membrane-bound enzyme system, the NADPH oxidase, these cells generate bactericidal metabolites. Activation of NADPH oxidase results in a generation of reactive oxygen species, e.g. READ MORE