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Showing result 1 - 5 of 32 swedish dissertations matching the above criteria.
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1. Exploring human variations by droplet barcoding
Abstract : Biological variations are being explored at ever-increasing rates through the rapid advancement of analytical techniques. Techniques like massively parallel sequencing empower scientists to accurately differentiate individuals’ genetic compositions, cellular functionalities, and healthy tissue from diseased. READ MORE
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2. Proximity Ligation and Barcoding Assays : Tools for analysis of proteins and protein complexes
Abstract : Proteins are fundamental structural, enzymatic and regulatory components of cells. Analysis of proteins, such as by measuring their concentrations, characterizing their modifications, and detecting their interactions, provides insights in how biological systems work physiologically or pathologically at the molecular level. READ MORE
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3. Taking a Bite out of Diversity - Taxonomy and systematics of biting midges
Abstract : The biting midges (family Ceratopogonidae) is one of the most species rich amongst the biting flies (Diptera) and has been recorded from most parts of the world. The species are mostly known for their capability to act as vectors for several important diseases, which have helped in shaping the focus to one of its genera, Culicoides Latreille, 1809. READ MORE
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4. It Takes Two to Tango : Bacterial heterogeneity and host cell features govern Salmonella infection
Abstract : Salmonella enterica serovar Typhimurium (S.Tm) causes enterocolitis with significant worldwide morbidity and mortality. The general aim of this thesis is to investigate variation in host cell invasion mechanisms used by S.Tm across different host cell contexts, as well as the influence of bacterial cell-cell heterogeneity on invasion-relevant S. READ MORE
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5. Technologies for Single Cell Genome Analysis
Abstract : During the last decade high throughput DNA sequencing of single cells has evolved from an idea to one of the most high profile fields of research. Much of this development has been possible due to the dramatic reduction in costs for massively parallel sequencing. READ MORE