Search for dissertations about: "basal forebrain"
Showing result 1 - 5 of 30 swedish dissertations containing the words basal forebrain.
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1. Anatomical, neurochemical and behavioural consequences of immunotoxin lesions of the basal forebrain cholinergic system
Abstract : The cholinergic hypothesis of geriatric memory dysfunction suggests that the learning and memory deficits representing the cardinal symptoms of dementia in the aged and in patients suffering from Alzheimer's disease may be attributable to a decline in the function of the cholinergic projection systems of the basal forebrain. Although many studies have addressed the issue of a causal relationship between cholinergic hypofunction and cognitive disturbance, analyses of the functional role of the basal forebrain cholinergic neuronal systems in the brain have so far been hampered by the lack of an efficient and specific cholinergic neurotoxin. READ MORE
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2. Specification of Dorsal and Intermediate Telencephalic Character
Abstract : The telencephalon is the most highly evolved region of the vertebrate central nervous system (CNS). The major structures of the telencephalon - the cortex and basal ganglia – derive from the dorsally positioned pallium and the ventrally positioned subpallium, respectively. READ MORE
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3. Computational Dissection of the Basal Ganglia : functions and dynamics in health and disease
Abstract : The basal ganglia (BG), a group of nuclei in the forebrain of all vertebrates, are important for behavioral selection. BG receive contextual input from most cortical areas as well as from parts of the thalamus, and provide output to brain systems that are involved in the generation of behavior, i.e. the thalamus and the brain stem. READ MORE
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4. On molecular mechanisms of neural differentiation and forebrain development
Abstract : Telencephalic development is an extraordinary complex process where neural structures of highly diverse cell compositions emerge as the result of multiple developmental strategies imposing tight regulation, balance and timing of gene expression. Embryonic telencephalic neural stem cells (NSCs) can form the major cell types found in the telencephalon, and are thus an excellent model for studying transcriptional control of lineage choice mechanisms in CNS development. READ MORE
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5. Phenotypic Specification of Striatal Progenitors; Evidence for both cell-autonomous and environmental control as studied by transplantation into the adult and developing rodent brain
Abstract : The striatum is the major component of the ventral telencephalon and basal ganglia, involved in the processing of cortical information. The vast majority of the neuronal population in the striatum are striatal projection neurons, with connection to the globus pallidus and substantia nigra. READ MORE
