Search for dissertations about: "base-pair breathing dynamics"

Found 1 swedish dissertation containing the words base-pair breathing dynamics.

2. 1. A biophysical study of nucleic acid interactions with analogues and drugs

   Author : Ulrica Sehlstedt; Donald M Crothers; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Nucleic acids; binding modes; polarised light spectroscopy; linear dichroism; NMR; triple helix; base-pair breathing dynamics; DAPI; porphyrins; quinoxaline derivatives; Biophysics; Biofysik; Biophysics; biofysik;

   Abstract : work presented in this thesis concerns studies on the physicochemical nature of interactions between nucleic acids and small ligands. The outcome of such studies can yield insights at a molecular level into the physiological mechanisms of action of biologically active nucleic-acid binding molecules. READ MORE