Search for dissertations about: "basement"

Showing result 11 - 15 of 147 swedish dissertations containing the word basement.

  2. 11. Surface proteins of Finegoldia magna interacting with the human host

    Author : Christofer Karlsson; Infektionsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Finegoldia magna; Gram-positive anaerobic cocci; surface proteins; protease; LL-37; MIG CXCL9; Fibrinogen; adhesion; gene disruption; bacterial aggregation; basement membranes;

    Abstract : Finegoldia magna is a Gram-positive anaerobe and a member of the normal human microflora. This bacterium is also an opportunistic pathogen and isolated from ~10% of all anaerobic infections. Reoccurring taxonomical changes and the anaerobic growth have contributed to the neglect of F. magna. READ MORE

  4. 12. Modulation of Angiogenesis by Laminins and Heparan Sulfate

    Author : Lars Jakobsson; Lena Claesson-Welsh; Johan Kreuger; Elisabetta Dejana; Uppsala universitet; []
    Keywords : Molecular medicine; Embryonic stem; heparan sulfate; laminin; basement membrane; VEGFR-2; VEGF; endothelial cell; signaling; angiogenesis; vasculogenesis; embryoid body; Molekylärmedicin;

    Abstract : Blood vessels transport blood with essential nutrients and oxygen to the cells in our body. In a healthy adult, formation of new vessels (angiogenesis) occurs only in case of tissue repair and growth. READ MORE

  5. 13. Laminins and alpha11 integrin in the human eye : importance in development and disease

    Author : Berit Byström; Fatima Pedrosa Domellöf; Ulf Stenevi; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; basement membranes; extracellular matrix; laminin; integrin; cornea; development; keratoconus; wound healing; remodeling; immunohistochemistry; Ophtalmiatrics; Oftalmiatrik;

    Abstract : The extracellular matrix (ECM) offers a protective shelter for cells and provides signaling paths important for cell to cell communication. ECM consists of basement membranes (BM) and interstitial matrix. BMs provide mechanical support for parenchymal cells, influence cell proliferation, survival, migration and differentiation. READ MORE

  6. 14. Stromal components and micro-RNAs as biomarkers in pancreatic cancer

    Author : Oskar Franklin; Malin Sund; Daniel Öhlund; Ola Billing; Marco Del Chiaro; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pancreatic cancer; stroma; basement membrane; tumour markers; type IV collagen; endostatin; osteopontin; tenascin c; hyaluronan; CD44; micro-RNA; kirurgi; Surgery;

    Abstract : Background Pancreatic ductal adenocarcinoma (PDAC) patients have the poorest 5-year survival rates of all cancer forms. It is difficult to diagnose at early disease stages, tumour relapse after surgery is common, and current chemotherapies are ineffective. READ MORE

  7. 15. Vascular remodelling and circulating basement membrane fragments in abdominal aortic aneurysm

    Author : Mari Holsti; Malin Sund; Anders Wanhainen; Joakim Nordanstig; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; AAA; extracellular matrix; vascular remodelling; collagen; inflammation; Surgery; kirurgi;

    Abstract : An abdominal aortic aneurysm (AAA) is a degenerative disease, characterized by advanced inflammation and extracellular matrix (ECM) remodelling. Enhanced protease activity mediated by cytokines results in the degradation of ECM proteins, leading to the generation of different bioactive fragments. READ MORE