Search for dissertations about: "basic human need"

Showing result 1 - 5 of 204 swedish dissertations containing the words basic human need.

  2. 1. Applying proteomics and metabolomics for studying human skeletal muscle with a focus on chronic trapezius myalgia

    Author : Jenny Hadrévi; Albert Crenshaw; Fatima Pedrosa-Domellöf; Fredrik Hellström; Bijar Ghafouri; Mary F Barbe; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Trapezius myalgia; proteomics; 2D-DIGE; metabolomics; microdialysate; biopsies; anatomi; Human Anatomy;

    Abstract : Work related musculoskeletal disorders are the dominating causes of reported ill-health in industrialized countries. These chronic pain conditions are one of the most costly public health problems in Europe and North America. READ MORE

  4. 2. Human papillomavirus and cellular biomarkers in cervical cancer

    Author : Malin Kaliff; Gabriella Lillsunde-Larsson; Mats G. Karlsson; Tina Dalianis; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cervical cancer; HPV; screening; triage; prognosis; genotype distribution; multiple HPV; HPV-negative; viral load; methylation;

    Abstract : Cervical cancer (CC) is caused by a persistent infection of certain types of the human papillomavirus (HPV). Even though great progress has been made in strategies for prevention, and treatment of CC, there is still a need for improved methods in screening and management of women diagnosed with CC. READ MORE

  5. 3. Repair of DNA double-stranded breaks in human cells

    Author : Susanne Nyström; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; DNA-PK; DNA double-stranded break; DSB; DNA single-stranded break; SSB; DNA damage; ionizing radiation; IR; DNA repair; calicheamicin gamma1; bleomycin; etoposide; topoisomerase II; radiotherapy; radiosensitizer; ATM;

    Abstract : DNA is continuously subjected to degradation. Therefore, our cells need to constantly repair its DNA to prevent mutations and in the long run cancer. In mammalian cells, when DNA is broken right off, a double-stranded break (DSB) is produced, and the ends are ligated by a process called non-homologous end-joining (NHEJ). READ MORE

  6. 4. CELL REPLACEMENT THERAPY FOR PARKINSON’S DISEASE: The importance of neuronal subtype, cell source and connectivity for functional recovery

    Author : Shane Grealish; Neurobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mouse behaviour; 6-hydroxydopamine; human embryonic stem cells; fetal tissue; connectivity; midbrain dopamine neuron subtype; cell transplantation; Parkinson’s disease;

    Abstract : Parkinson’s disease (PD) is a neurodegenerative disorder characterised by motor deficits such as slowness in movement, difficulty in initiating movement and tremor at rest. The cause of these motor symptoms is the selective loss of mesencephalic dopaminergic (mesDA) neurons, located in the substantia nigra (SN). READ MORE

  7. 5. Impact of Interleukin-6 family cytokine signalling on human endothelial cells and platelets

    Author : Madelene Lindkvist; Magnus Grenegård; Liza Ljungberg; Alistair W. Poole; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; gp130 signalling cytokines; inflammation; transsignalling; JAK STAT; MEK ERK; PI3K AKT; platelet aggregation; vasodilation;

    Abstract : Endothelial cells lining the luminal side of blood vessels creates a barrier between the circulating blood and the extracellular matrix. Endothelial cells have important functions in regulation of vessel tension and inflammation. READ MORE