Search for dissertations about: "bc1-2"

Found 2 swedish dissertations containing the word bc1-2.

  2. 1. Development of squamous cell carcinoma in venous ulcers

    Author : Baldur Baldursson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : cancer epidemiology; human papillomavirus; p53; p21; bc1-2; Ki-67; wound healing; chronic ulcers; skin carcinogenesis; growth factors;

    Abstract : Apart from numerous case reports, studies on the epidemiology and the outcome of malignant transformation in venous leg ulcers are scarce. Even the aetiology is unsettled, and the genetic effects of the chronic ulcer state only partly studied. READ MORE

  4. 2. The antagonistic role of activated oncogenes and apoptosis : studies of n-myc and p53 in lymphoid tumorigenesis

    Author : Yisong Wang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MPC; EmyN-myc transgene; J3D T Iymphoma cells; p53; v-m y cretrovirus; bcl-2; Gl cell cycle arrest; apoptosis; HPV 16 E7;

    Abstract : Inactivation of the p53 tumor suppressor gene and activation of proto-oncogenes have been implicated in the initiation and/or progression of a number of neoplasms. In this thesis, the involvement of N-myc gene activation has been studied in mouse plasmacytomagenesis and the role of wild-type (wt)p53 and oncogene activation has been evaluated with particular emphasis on apoptosis. READ MORE