Search for dissertations about: "bcl-2"

Showing result 6 - 10 of 137 swedish dissertations containing the word bcl-2.

  2. 6. Apoptosis And Excitotoxicity In The Death of Cultured And Grafted Dopaminergic Neurones

    Author : Gabriele Schierle; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ac-YVAD-cmk; MK-801; flunarizine; N-methyl-D-aspartate; voltage-dependent calcium channels; Bcl-2; caspase; excitotoxicity; apoptosis; tyrosine hydroxylase; dopamine; Parkinson s disease; intracerebral transplantation; Poly ADP-ribose polymerase; Neurology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi;

    Abstract : Over the past two decades, grafting of embryonic nigral tissue has developed into a feasible therapeutic strategy for Parkinson's disease (PD). It has become apparent that the degree of restoration of dopaminergic neurotransmission by the transplanted cells is highly correlated to the symptomatic relief. READ MORE

  4. 7. Regulation of Apoptosis in Hematopoietic Progenitor Cells: Involvement of Different Signaling Pathways

    Author : Maria Kraft; Institutionen för translationell medicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cytokines; apoptosis; cell cycle; c-Kit; Flt3; Flt3-ITD; Akt; Bcl-2; FoxO3; mouse; hematopoiesis; progenitor;

    Abstract : Proliferation, differentiation, and survival of hematopoietic stem cells and multipotent progenitor cells are regulated by cytokines and cell-cell interactions. Kit ligand (KL) and Flt3 ligand (FL) have pleiotropic effects, promotes survival, but are nonredundant. READ MORE

  5. 8. Diffuse large B-cell lymphoma – studies on immunohistochemical and clinical prognostic factors

    Author : Sverker Hasselblom; Göteborgs universitet; []
    Keywords : DLBCL; prognosis; sex; population-based; apoptosis; Ki-67; CTLs; TIA-1; FOXP3; bcl-2; GCB; p-AKT;

    Abstract : DLBCL, the most common lymphoma entity, is a potentially curable but heterogeneous disease. Most studies concerning therapy and prognostic factors have been performed on selected patient materials. It is important to identify immunohistochemical biomarkers which could add prognostic information to clinical factors. READ MORE

  6. 9. Anti-Apoptotic Proteins in Nerve Cell Survival and Neurodegeneration

    Author : Laura Korhonen; Marja Jäättelä; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; neuronal cell death; XIAP; RIAP-2; Hippocalcin; Bcl-2; Bcl-X; kainic acid; DRG; estrogen; Neurovetenskap; Neurology; Neurologi; Developmental Neurosciences; medicinsk utvecklings- och neurobiologi;

    Abstract : Apoptosis is a genetically regulated cell death program, which shows distinct morphological characteristics. It takes place during neuronal development and in some neurodegenerative diseases. During apoptosis, the intracellular proteins are degraded by various caspases, cysteine aspartases, which are regulated by pro- and anti-apoptotic signals. READ MORE

  7. 10. Aspects of the human enteric nervous system : A study of the normal development and of Hirschsprung's disease

    Author : Tomas Wester; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; enteric nervous system; Hirschsprung s disease; intestinal neuronal dysplasia; neuron density; nitric oxide; bcl-2; interstitial cells of Cajal; c-kit; human; fetal; development; Kirurgi; Surgery; Kirurgi; Surgery; kirurgi;

    Abstract : Thirty patients with Hirschsprung's disease (HD) who underwent Rehbein's anterior resection, using a circular stapler to perform the anastomosis, were evaluated retrospectively. The postoperative complication rate and long-term functional outcome were similar to those reported by other investigators using the same and other techniques. READ MORE