Search for dissertations about: "benign prostatic hyperplasia BPH"
Showing result 11 - 13 of 13 swedish dissertations containing the words benign prostatic hyperplasia BPH.
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11. LXR and aromatase knock-out mice : animal models providing insight into human diseases
Abstract : In our characterization of mouse strains carrying mutations in nuclear receptor and aromatase genes we have found phenotypes which resemble four human diseases: benign prostatic hyperplasia (BPH), Sjögren s syndrome (SS), amyotrophic lateral sclerosis (ALS), and exocrine pancreatic insufficiency. The work in this thesis was designed to understand the roles of LXRalpha, LXRbeta and aromatase in development of these diseases and to investigate whether these animal models help us (1) to understand the etiology of the corresponding human diseases and (2) to develop new therapeutic approaches for the treatment of these diseases. READ MORE
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12. Human glandular kallikrein 2 (hK2) in prostate cancer: Clinical and Methodological studies
Abstract : Human glandular kallikrein 2 (hK2) is a predominantly prostate produced protein with many similarities to prostate-specific antigen (PSA). Just like for PSA elevated levels of hK2 can be found in men with protate cancer. We created an assay where hK2 in serum could reliably and with negligible cross-reactivity with PSA, be measured down to 0. READ MORE
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13. Harnessing urinary extracellular vesicles microRNA by acoustic trapping as potential biomarkers for prostate cancer
Abstract : Prostate cancer (PCa) is an interesting study case of clinical management of uncertainty. PCa is the most diagnosed but only the second-leading cause of non-cutaneous cancer-related mortalities among men in developed countries. To put simply, the life-time risk of PCa diagnosis and mortality is approximately 11% and 3% respectively; a ~3. READ MORE
