Search for dissertations about: "benzodiazepine"

Showing result 16 - 20 of 39 swedish dissertations containing the word benzodiazepine.

  1. 16. Bioanalytical studies of designer benzodiazepines

    Author : Madeleine Pettersson Bergstrand; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The fast appearance of benzodiazepine analogues, referred to as new psychoactive substance (NPS) or designer benzodiazepines, requires the continuous update of detection methods in order to keep up with the latest drugs on the recreational drug market. Moreover, as usually only limited information on toxicity and excretion patterns of these new drugs exists, this needs to be evaluated to report on adverse effects and to determine suitable targets for drug testing. READ MORE

  2. 17. Epidemiological studies of medication use and effectiveness in bipolar disorder

    Author : Louise Wingård; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : In the last decades, new treatments for bipolar disorder (BD) have emerged, prompting a decrease in the use of lithium – the former “gold standard” for relapse prevention, and increasing the possibilities for individualized treatment. The aims of this thesis were to: 1) explore the use of relapse prevention in the early phases of bipolar illness, 2) add to the current knowledge concerning the comparative effectiveness of various pharmacological maintenance treatments, including combination therapies, and 3) explore the use of benzodiazepines and non-benzodiazepine hypnotics (so called Z-drugs) in BD. READ MORE

  3. 18. Placebo, alcohol and flumazenil provocations : subjective and objective registrations in psychopharmacological experiments

    Author : Lars Saxon; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Abuse and dependency of alcohol or drugs is a major problem today, with severe implications for society as well as for the individual. Treatment is often characterised by hard work and the road to recovery is (among other problems) paved with acute and protracted withdrawal symptoms as well as relapse. READ MORE

  4. 19. Statistics on local drug sales: A tool to identify problem areas and to follow effects of education on drug use

    Author : Anders Ekedahl; Kardiovaskulär forskning - epidemiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; unused drugs; Pharmacological sciences; toxikologi; farmaci; farmakognosi; Farmakologi; toxicology; pharmacognosy; pharmacy; producer independent information; drug sales statistics;

    Abstract : Aims: 1) To assess if drug sales data indicate differences in morbidity, mortality, socio-economic conditions and deviating prescribing habits among physicians; 2) to identify areas for educational interventions and to analyse changes in prescribing after educational activities. In addition, an effort was made to estimate differences between pharmacy sales and purchases by the population, and the amount and value of unused drugs returned to pharmacies. READ MORE

  5. 20. Register-based studies of delivery outcome after maternal use of some common drugs

    Author : Birgitta Norstedt Wikner; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : This thesis aimed to study neonatal outcome including the presence of congenital malformations and to describe maternal characteristics for women using some common drugs during pregnancy. Drugs used in one benign condition (nausea and vomiting) and one chronic disease (hypothyroidism) and the CNS-active drugs benzodiazepines and hypnotic benzodiazepine receptor agonists were selected. READ MORE