Search for dissertations about: "beta cells"

Showing result 11 - 15 of 630 swedish dissertations containing the words beta cells.

  2. 11. Beta Camera: Development and applications

    Author : Kaj Ljunggren; Lund Medicinsk strålningsfysik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk fysiologi; radiologi; tomografi; medicinsk instrumentering; medical instrumentation; tomography; radiology; Clinical physics; microchannel plate; radionuclides; scintillator; autoradiography; Beta Camera;

    Abstract : A new detector for on-line digital detection of charged particles (beta-particles, conversion electrons and alpha-particles) from thin samples for rapid autoradiography has been developed; the Beta Camera. The device consists of a photon-sensitive detector (image photon detector, IPD); the main component of which is a microchannel plate. READ MORE

  4. 12. Exocytosis in Type 2 Diabetes- Functional and genetic studies of hormone secretion

    Author : Sofia A Andersson; Diabetes - öcellsexocytos; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 2 Diabetes; Insulin; Glucagon; Alpha-cells; Beta-cells; Exocytosis; Capacitance; SNARE; SNAP25; Syntaxin1A; Synaptotagmin; Munc-18 Stxbp1 ; SNP; Expression; miRNA;

    Abstract : Type 2 Diabetes (T2D) is characterized by dysregulated beta-and alpha-cell hormone secretion leading to elevated blood glucose levels. Several proteins are crucial in maintaining exocytosis of the hormone-containing granules such as Syntaxin1A (Stx1A), SNAP25, Munc-18 (Stxbp1) and the family of Synaptotagmins (Syts). READ MORE

  5. 13. In vivo and in vitro approaches to induce beta cells from stem and progenitor cells

    Author : Lars Selander; Helena Edlund; Yuval Dor; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pancreas; stem cell; progenitor; beta cell; in vitro; Molecular medicine genetics and pathology ; Molekylär medicin genetik och patologi ; molecular medicine medical sciences ; molekylär medicin medicinska vetenskaper ;

    Abstract : Diabetes or diabetes mellitus which is the correct medical term is a medical condition were the affected person lack the ability to regulate his or her blood glucose levels. This inability is directly due to the fact that the insulin producing cells, residing in the pancreas, can’t meet the body’s demand for insulin. READ MORE

  6. 14. Lipid metabolism in the pancreatic beta-cell. Implications for insulin secretion

    Author : Malin Fex; Celiaki och diabetes; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetology; Endokrinologi; sekretion; diabetologi; Endocrinology; secreting systems; Lipid metabolism; Insulin secretion; Beta-cells;

    Abstract : We have investigated the role of lipid metabolism with regard to beta-cell function and insulin secretion. Lipids are known to play a crucial functional role in the pancreatic beta-cell, where they are essential for adequate hormone release, but may also exert a long-term toxic effect, leading to beta-cell dysfunction. READ MORE

  7. 15. Mitochondrial form and function in pancreatic β-cells and brown adipocytes

    Author : Jakob D Wikström; Jan Nedergaard; Roberta Gottlieb; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mitochondria; beta cells; brown adipose tissue; diabetes; obesity; Physiology; Fysiologi; fysiologi; Physiology;

    Abstract : This thesis is focused on the role of mitochondria in pancreatic β-cells and brown adipose tissue (BAT). Two main aspects of mitochondria were explored; mitochondrial functional efficiency and the interrelationship between mitochondrial shape and function. READ MORE